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Results for "(E)-Necrosulfonamide" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-100573
    (E)-Necrosulfonamide

    Mixed Lineage Kinase Cancer
    (E)-Necrosulfonamide is a necroptosis inhibitor acting by selectively targeting the mixed lineage kinase domain-like protein (MLKL). MLKL is a critical substrate of RIP3 during the induction of necrosis. (E)-Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors.