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(R)-Citalopram-d6

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99

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6937
    (R,R)-Secoisolariciresinol diglucoside

    (R,R)-SDG; (R,R)-LGM2605

    		 Others Inflammation/Immunology
    (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .
    (<em>R</em>,<em>R</em>)-Secoisolariciresinol diglucoside
  • HY-15344
    (R,R)-BD-AcAc 2
    1 Publications Verification

    (R,R)-Ketone Ester

    		 Others Neurological Disease Metabolic Disease
    (R,R)-BD-AcAc 2 ((R,R)-Ketone Ester), a ketone monoester, can be used as a source of oral nutritional ketones. (R,R)-BD-AcAc 2 can elevate plasma levels of β-hydroxybutyrate and acetoacetate, blood glucose, blood Na + levels and blood creatinine levels after oral administration in mice. (R,R)-BD-AcAc 2 can partly prevent muscle weakness in septic mice. (R,R)-BD-AcAc 2 has potential to improve exercise performance and endurance in animal body. (R,R)-BD-AcAc 2 can also be used to research Parkinson’s disease or diabetes .
    (<em>R</em>,<em>R</em>)-BD-AcAc 2
  • HY-14645A
    (+)-DHMEQ
    2 Publications Verification

    (1R,2R,6R)-Dehydroxymethylepoxyquinomicin; (1R,2R,6R)-DHMEQ

    		 Keap1-Nrf2 Inflammation/Immunology
    (+)-DHMEQ is an activator of antioxidant transcription factor Nrf2. (+)-DHMEQ is the enantiomer of (-)-DHMEQ. (-)-DHMEQ inhibits NF-kB than its enantiomer (+)-DHMEQ.
    (+)-DHMEQ
  • HY-B0761
    (R,R)-Glycopyrrolate

    (R,R)-Glycopyrronium bromide; (R,R)-Glycopyrrolate bromide

    		 mAChR Neurological Disease
    (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) is an anticholinergic agent. (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) has the ability to reduce the frequency of drooling in vivo with developmental disabilities .
    (<em>R</em>,<em>R</em>)-Glycopyrrolate
  • HY-14560A
    (R,R)-Reboxetine mesylate

    (R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate

    		 Adrenergic Receptor mAChR Neurological Disease
    (R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals .
    (<em>R</em>,<em>R</em>)-Reboxetine mesylate
  • HY-75087
    (R)-pyrrolidine-2-carboxylic acid

    (+)-(R)-Proline; (R)-(+)-Proline; (R)-2-Carboxypyrrolidine; (R)-Proline

    		 Endogenous Metabolite Metabolic Disease
    (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.
    (<em>R</em>)-pyrrolidine-2-carboxylic acid
  • HY-U00092B
    (R,R)-BAY-Y 3118

    		Bacterial Infection
    (R,R)-BAY-Y 3118 is the R-enantiomer of BAY-Y 3118. (R,R)-BAY-Y 3118 shows weak bactericidal activity .
    (<em>R</em>,<em>R</em>)-BAY-Y 3118
  • HY-137453C
    (R,1R)-Tenofovir amibufenamide

    (R,1R)-HS-10234

    		 Others Others
    (R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used for the purifying a tenofovir prodrug. Tynofovir (tenofovir) is a nucleoside acids reverse transcriptase inhibitors .
    (<em>R</em>,1<em>R</em>)-Tenofovir amibufenamide
  • HY-76542B
    (R)-Vitamin D2

    (R)-Ergocalciferol; (R)-Calciferol; (R)-Ercalciol

    		 Others Metabolic Disease Cancer
    (R)-Vitamin D2 is the isomer of Vitamin D2 (HY-76542), and can be used as an experimental control. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D .
    (<em>R</em>)-Vitamin D2
  • HY-A0021C
    (R,R)-Palonosetron Hydrochloride

    		5-HT Receptor Inflammation/Immunology
    (R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron.
    (<em>R</em>,<em>R</em>)-Palonosetron Hydrochloride
  • HY-59125
    (R,R)-(+)-Hydrobenzoin

    		Endogenous Metabolite Others
    (R,R)-(+)-Hydrobenzoin is a organocatalysts .
    (<em>R</em>,<em>R</em>)-(+)-Hydrobenzoin
  • HY-103451
    (R,R)-THC

    		Estrogen Receptor/ERR Metabolic Disease
    (R,R)-THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R,R)-THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6 .
    (<em>R</em>,<em>R</em>)-THC
  • HY-17554
    (R)-Oxiracetam

    (R)-(+)-Oxiracetam; (R)-ISF2522

    		 Others Neurological Disease
    (R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam.
    (<em>R</em>)-Oxiracetam
  • HY-116463C
    (2R,3R)-E1R

    		Sigma Receptor Neurological Disease
    (2R,3R)-E1R (Compound 2b) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders .
    (2<em>R</em>,3<em>R</em>)-E1<em>R</em>
  • HY-13986A
    (R)-Merimepodib

    (R)-VX-497; (R)-MMPD

    		 Others Infection
    (R)-Merimepodib is the isomer of Merimepodib (HY-13986), and can be used as an experimental control. Merimepodib (VX-497) is a noncompetitive and oral inhibitor of inosine monophosphate dehydrogenase (IMPDH) with broad spectrum antiviral activities.
    (<em>R</em>)-Merimepodib
  • HY-16723A
    (R)-Funapide

    (R)-TV 45070; (R)-XEN402

    		 Sodium Channel Neurological Disease
    (R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. Funapide is a potent Nav1.7 sodium channel blocker that can be used for pain research .
    (<em>R</em>)-Funapide
  • HY-110258B
    (R,S,R)-ML334

    (R,S,R)-LH601A

    		 Others Cancer
    (R,S,R)-ML334 is the isomer of ML334 (HY-110258), and can be used as an experimental control. ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity .
    (<em>R</em>,S,<em>R</em>)-ML334
  • HY-103320B
    (1R,2R)-Calhex 231 hydrochloride

    		Others Metabolic Disease
    (1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca 2+-induced accumulation of [ 3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment .
    (1<em>R</em>,2<em>R</em>)-Calhex 231 hydrochloride
  • HY-13631J
    (1R,9R)-Exatecan mesylate

    (1R,9R)-DX8951f

    		 Topoisomerase Cancer
    (1R,9R)-Exatecan mesylate((1R,9R)-DX8951f) is an isomer of Exatecan mesylate (HY-13631A). Exatecan mesylate (DX8951f) is an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM (0.975 μg/mL) and can be used in cancer research .
    (1<em>R</em>,9<em>R</em>)-Exatecan mesylate
  • HY-16940A
    24(R)-Hydroxycholesterol

    24R-OHC; 24R-HC; 24(R)-Cerebrosterol

    		 Others Others
    24(R)-Hydroxycholesterol (24R-OHC) is a key intermediate of Tacalcitol (HY-32337) .
    24(<em>R</em>)-Hydroxycholesterol
  • HY-B0006C
    (R)-Carvedilol

    (R)-BM 14190

    		 Adrenergic Receptor Cardiovascular Disease
    (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX) .
    (<em>R</em>)-Carvedilol
  • HY-B0352B
    (R)-Mirtazapine

    (R)-Org3770; (R)-6-Azamianserin

    		 5-HT Receptor Neurological Disease
    (R)-Mirtazapine ((R)-Org3770) is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4 .
    (<em>R</em>)-Mirtazapine
  • HY-13079
    Cobimetinib (R-enantiomer)

    GDC-0973 (R-enantiomer); XL-518 (R-enantiomer)

    		 MEK Cancer
    Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor.
    Cobimetinib (<em>R</em>-enantiomer)
  • HY-12279F
    Umbralisib R-enantiomer

    TGR-1202 R-enantiomer; RP5264 R-enantiomer
    Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202.
    Umbralisib <em>R</em>-enantiomer
  • HY-B1178A
    R-(+)-Cotinine

    (+)-Cotinine; (R)-Cotinine; (R)-NIH-10498

    		 nAChR Neurological Disease
    R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs .
    <em>R</em>-(+)-Cotinine
  • HY-12866B
    (R)-Larotrectinib

    (R)-LOXO-101; (R)-ARRY-470

    		 Trk Receptor Infection Inflammation/Immunology Cancer
    (R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases
    (<em>R</em>)-Larotrectinib
  • HY-15584C
    (R)-Taltobulin

    (R)-HTI-286; (R)-SPA-110

    		 Others Others
    (R)-Taltobulin ((R)-HTI-286) can be used as a reference substance .
    (<em>R</em>)-Taltobulin
  • HY-10261E
    (R)-Afatinib

    (R)-BIBW 2992

    		 EGFR c-Met/HGFR p38 MAPK Cancer
    (R)-Afatinib ((R)-BIBW 2992) is the Afatinib isomer. Afatinib (HY-10261) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt, EGFR L858R, EGFR L858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer .
    (<em>R</em>)-Afatinib
  • HY-17623C
    (R)-Tegoprazan

    (R)-CJ-12420; (R)-RQ-00000004

    		 Proton Pump Metabolic Disease
    (R)-Tegoprazan (example 3), a benzimidazole derivative, is a potent kidney H +/K +-ATPase inhibitor with an IC50 of 98 nM of canine kidney Na +/K +-ATPase. (R)-Tegoprazan has the potential for gastrointestinal diseases research .
    (<em>R</em>)-Tegoprazan
  • HY-15743A
    (R)-Birabresib

    (R)-OTX-015; (R)-MK-8628

    		 Others Cancer
    (R)-Birabresib is the isomer of Birabresib (HY-15743), and can be used as an experimental control. Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM.
    (<em>R</em>)-Birabresib
  • HY-139553A
    (R)-Zunsemetinib

    (R)-ATI-450; (R)-CDD-450

    		 Others Inflammation/Immunology
    (R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553), and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases .
    (<em>R</em>)-Zunsemetinib
  • HY-78931E
    (R,S,R,S,R)-Boc-Dap-NE

    		Others Cancer
    (R,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    (<em>R</em>,S,<em>R</em>,S,<em>R</em>)-Boc-Dap-NE
  • HY-78131B
    (R)-(-)-Ibuprofen
    2 Publications Verification

    (R)-Ibuprofen

    		 NF-κB Inflammation/Immunology Cancer
    (R)-(-)-Ibuprofen is the R enantiomer of Ibuprofen, inactive on COX, inhibits NF-κB activation; (R)-(-)-Ibuprofen exhibits anti-inflammatory and antinociceptive effects.
    (<em>R</em>)-(-)-Ibuprofen
  • HY-100615A
    R 80123

    		Phosphodiesterase (PDE) Cardiovascular Disease
    R 80123 is the Z-isomer of R 79595, is also a highly selective phosphodiesterase inhibitor.
    <em>R</em> 80123
  • HY-N0221
    Daurisoline
    2 Publications Verification

    (R,R)-Daurisoline

    		 Autophagy Potassium Channel Cancer
    Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .
    Daurisoline
  • HY-14658B
    (R)-Thalidomide

    (R)-(+)-Thalidomide

    		 Others Metabolic Disease
    (R)-Thalidomide ((R)-(+)-Thalidomide) is the R-enantiomer of Thalidomide. (R)-Thalidomide has psychomotor stabilizing properties .
    (<em>R</em>)-Thalidomide
  • HY-135336
    (R)-Verapamil hydrochloride

    (R)-(+)-Verapamil hydrochloride

    		 P-glycoprotein Apoptosis Cancer
    (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents .
    (<em>R</em>)-Verapamil hydrochloride
  • HY-B1370B
    (R)-Hydroxychloroquine

    (R)-HCQ

    		 Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy Infection
    (R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine . Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .
    (<em>R</em>)-Hydroxychloroquine
  • HY-109854A
    (R)-Lisofylline

    (R)-Lisophylline

    		 STAT Metabolic Disease Inflammation/Immunology
    (R)-Lisofylline ((R)-Lisophylline) is a (R)-enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R)-Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 µM and interrupts IL-12 signaling-mediated STAT4 activation. (R)-Lisofylline has the potential for type 1 diabetes, autoimmune disorders research .
    (<em>R</em>)-Lisofylline
  • HY-128888
    (R,R)-GSK321

    		Isocitrate Dehydrogenase (IDH) Cancer
    (R,R)-GSK321 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC50 value of 120 nM. (R,R)-GSK321 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity .
    (<em>R</em>,<em>R</em>)-GSK321
  • HY-D0988
    R-PE (R-Phycoerythrin)

    		Fluorescent Dye Others
    R-Phycoerythrin is a phycobiliproteins could be isolated from Heterosiphonia japonica. R-Phycoerythrin is a potent fluorescent probe contains four chromophore-carrying subunits that exhibits extremely bright red-orange fluorescence. (λex=496 nm, λem=578 nm) .
    <em>R</em>-PE (<em>R</em>-Phycoerythrin)
  • HY-151385A
    (R,R)-VVD-118313

    		STAT Interleukin Related IFNAR JAK Cancer
    (R,R)-VVD-118313 is the isomer of VVD-118313 (HY-151385). VVD-118313 is a selective JAK1 inhibitor and blocks JAK1-dependent trans-phosphorylation and cytokine signaling. VVD-118313 can be used for research of cancer . (R,R)-VVD-118313 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (<em>R</em>,<em>R</em>)-VVD-118313
  • HY-100741C
    (R,R)-S63845

    		Others Cancer
    (R,R)-S63845 is the isomer of S63845 (HY-100741), and can be used as an experimental control. S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1 .
    (<em>R</em>,<em>R</em>)-S63845
  • HY-P1285
    Conantokin R

    Con-R

    		 iGluR Neurological Disease
    Conantokin R (Con-R) is an NMDA receptor peptide antagonist with an IC50 of 93 nM. Conantokin R binds Zn 2+ and Mg 2+ with Kds of 0.15 μM and 6.5 μM, respectively. Conantokin R shows anticonvulsant activity .
    Conantokin <em>R</em>
  • HY-136285A
    (R,R)-CPI-1612

    		Others Cancer
    (R,R)-CPI-1612 is the isomer of CPI-1612 (HY-136285), and can be used as an experimental control. CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity .
    (<em>R</em>,<em>R</em>)-CPI-1612
  • HY-10013B
    Taranabant ((1R,2R)stereoisomer)

    MK0364 (1R,2R)stereoisomer

    		 Cannabinoid Receptor Others
    Taranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant. Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist.
    Taranabant ((1<em>R</em>,2<em>R</em>)stereoisomer)
  • HY-W001069
    RuCl(p-cymene)[(R,R)-Ts-DPEN]

    RuCl[(R,R)-Tsdpen](p-cymene)

    		 Biochemical Assay Reagents Others
    RuCl(p-cymene)[(R,R)-Ts-DPEN] is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    RuCl(p-cymene)[(<em>R</em>,<em>R</em>)-Ts-DPEN]
  • HY-137440B
    (2R,3R)-Firazorexton

    (2R,3R)-TAK-994 free base

    		 Orexin Receptor (OX Receptor) Neurological Disease
    (2R,3R)-Firazorexton ((2R,3R)-TAK-994 free base) is an isomer of Firazorexton (HY-137440). Firazorexton is an orally active, brain-penetrating orexin type 2 receptor (OX2R) agonist that may improve narcolepsy-like symptoms ..
    (2<em>R</em>,3<em>R</em>)-Firazorexton
  • HY-17044A
    Duvelisib (R enantiomer)

    IPI-145 R enantiomer; INK1197 R enantiomer

    		 PI3K Cancer
    Duvelisib R enantiomer is a PI3K inhibitor, which is the less active enantiomer of Duvelisib.
    Duvelisib (<em>R</em> enantiomer)
  • HY-W051723
    (R)-3-Hydroxybutanoic acid
    3 Publications Verification

    (R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid

    		 Endogenous Metabolite Others
    (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones .
    (<em>R</em>)-3-Hydroxybutanoic acid

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