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(Rac)-cis-Ambroxol-d5

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98

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2

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Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-U00360

    (Rac)-Netazepide; (Rac)-YF 476; (Rac)-YM-220

    Cholecystokinin Receptor Metabolic Disease
    (Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.
    (<em>Rac</em>)-Sograzepide
  • HY-76688

    (Rac)-ARQ 197; (Rac)-ARQ 198

    Others Cancer
    (Rac)-Tivantinib is the isomer of Tivantinib (HY-50686), and can be used as an experimental control. Tivantinib is a highly selective c-Met tyrosine kinase inhibitor with a Ki of 355 nM.
    (<em>Rac</em>)-Tivantinib
  • HY-N0106

    (Rac)-Danshensu sodium; (Rac)-Tanshinol sodium

    Others Others
    (Rac)-Salvianic acid A sodium is the racemate of Salvianic acid A (HY-N1913). Salvianic acid A, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
    (<em>Rac</em>)-Salvianic acid A sodium
  • HY-N6030

    (Rac)-Dencichin; (Rac)-ODAP

    HIF/HIF Prolyl-Hydroxylase Others
    (Rac)-Dencichine ((Rac)-Dencichin) is the racemate of Dencichin. Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity .
    (<em>Rac</em>)-Dencichine
  • HY-113145

    (Rac)-Danshensu; (Rac)-Tanshinol

    Others Others
    (Rac)-Salvianic acid A is the racemate of Salvianic acid A (HY-N1913). Salvianic acid A, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
    (<em>Rac</em>)-Salvianic acid A
  • HY-N0278A

    (Rac)-Pulsatilla camphor; (Rac)-Anemonine

    (Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
    (<em>Rac</em>)-Anemonin
  • HY-13728B

    (Rac)-ZD 9331; (Rac)-BGC9331

    Thymidylate Synthase Cancer
    (Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331)?is a racemate of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor. (Rac)-Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (<em>Rac</em>)-Plevitrexed
  • HY-107526

    (Rac)-NFPS

    GlyT Neurological Disease
    NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively . NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion .
    (<em>Rac</em>)-ALX 5407
  • HY-119486A

    (Rac)-PF-06649751; (Rac)-CVL-751

    Dopamine Receptor Arrestin Neurological Disease
    (Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP, EC50=0.8 nM; β-arrestin2, EC50=68 nM). (Rac)-Tavapadon has antiparkinsonian activity .
    (<em>Rac</em>)-Tavapadon
  • HY-B0203B

    (Rac)-R 065824

    Adrenergic Receptor NADPH Oxidase Cardiovascular Disease
    (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity .
    (<em>Rac</em>)-Nebivolol
  • HY-14881B

    (Rac)-TMC207; (Rac)-R207910

    Others Infection
    (Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
    (<em>Rac</em>)-Bedaquiline
  • HY-15251A

    (Rac)-Repertaxin; (Rac)-DF 1681Y

    Others Inflammation/Immunology Endocrinology Cancer
    (Rac)-Reparixin is the isomer of Reparixin (HY-15251), and can be used as an experimental control. Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC50s of 1 and 100 nM, respectively.
    (<em>Rac</em>)-Reparixin
  • HY-N0585

    (Rac)-NCTD

    Endogenous Metabolite Cancer
    (Rac)-Norcantharidin ((Rac)-NCTD) is the isoform of Norcantharidin, which is a synthetic and demethylated anticancer agent derived from Cantharidin (HY-N0209). Norcantharidin has lighter side effects and stronger bioactivity than Cantharidin. And Norcantharidin inhibits cell proliferation, migration and metastasis, and causes apoptosis and autophagy .
    (<em>Rac</em>)-Norcantharidin
  • HY-75124
    (Rac)-AZD 6482
    1 Publications Verification

    (Rac)-KIN-193

    PI3K Autophagy Cancer
    (Rac)-AZD 6482 ((Rac)-KIN-193) is the racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
    (<em>Rac</em>)-AZD 6482
  • HY-U00401

    (Rac)-LNK-754; (Rac)-OSI-754

    Farnesyl Transferase Others
    (Rac)-CP-609754 is the racemate of CP-609754. CP-609754 is a farnesyltransferase inhibitor, used for the treatment of cancer and Alzheimer's disease.
    (<em>Rac</em>)-CP-609754
  • HY-76570

    (Rac)-Desfesoterodine; (Rac)-PNU-200577

    mAChR Neurological Disease
    (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine can be used for overactive bladder research .
    (<em>Rac</em>)-5-Hydroxymethyl Tolterodine
  • HY-76570A

    (Rac)-Desfesoterodine hydrochloride; (Rac)-PNU-200577 hydrochloride

    mAChR Neurological Disease
    (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) hydrochloride, an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine hydrochloride can be used for overactive bladder research .
    (<em>Rac</em>)-5-Hydroxymethyl Tolterodine hydrochloride
  • HY-101202A

    (Rac)-NIH 10815

    Opioid Receptor Neurological Disease
    (Rac)-SNC80 is a racemate of SNC80 (HY-101202). SNC80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist with a Ki of 1.78 nM and an IC50 of 2.73 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant‐like effects. SNC80 has the potential for multiple headache disorders treatment .
    (<em>Rac</em>)-SNC80
  • HY-150617A

    (Rac)-M4076; (Rac)-ATM Inhibitor-5

    ATM/ATR Cancer
    (Rac)-Lartesertib ((Rac)-M4076; (Rac)-ATM Inhibitor-5) is an isoform of Lartesertib (HY-150617), which is a potent inhibitor of serine/threonine protein kinase ATM (extracted from patent WO2022058351A1) .
    (<em>Rac</em>)-Lartesertib
  • HY-N5112

    (Rac)-β,β-Dimethylacrylalkannin; (Rac)-β,β-​Dimethylacrylshikonin

    HIF/HIF Prolyl-Hydroxylase Others
    (Rac)-Arnebin 1 ((Rac)-β,β-Dimethylacrylalkannin) is the racemate of β,β-Dimethylacrylalkannin and/or β,β-Dimethylacrylshikonin. β,β-Dimethylacrylalkannin and β,β-Dimethylacrylshikonin are napthoquinones isolated from Arnebia nobilis. β,β-Dimethylacrylshikonin has anti-tumor activity .
    (<em>Rac</em>)-Arnebin 1
  • HY-104065A

    (Rac)-SHR-1258

    Others Cancer
    (Rac)-Pyrotinib ((Rac)-SHR-1258) is the racemate of Pyrotinib (HY-104065). Pyrotinib is a potent and selective EGFR/HER2 dual inhibitor.
    (<em>Rac</em>)-Pyrotinib
  • HY-108235B

    (Rac)-AZD6765

    iGluR Neurological Disease
    (Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .
    (<em>Rac</em>)-Lanicemine
  • HY-141411

    (Rac)-MRI-1867

    Cannabinoid Receptor NO Synthase Others
    (Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a cannabinoid receptor type 1 (CB1R)/iNOS antagonist, with a Ki of 5.7 nM for CB1R. (Rac)-Zevaquenabant is potential for the research of liver fibrosis .
    (<em>Rac</em>)-Zevaquenabant
  • HY-100540A

    (Rac)-GCA

    Enterovirus Infection
    (Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
    (<em>Rac</em>)-Golgicide A
  • HY-144841A

    (Rac)-CFT7455

    Others Cancer
    (Rac)-Cemsidomide ((Rac)-CFT7455) is a zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) degrader, acting via the ubiquitin proteasome pathway, with a GI50 of 0.05 nM for NCIH929.1 cells. (Rac)-Cemsidomide is the racemic isomer of Cemsidomide (HY-144841A) which is a IKZF1/IKZF3 degrader with anticancer activity .
    (<em>Rac</em>)-Cemsidomide
  • HY-139573A

    (Rac)-FT-4202

    Pyruvate Kinase Cardiovascular Disease
    (Rac)-Etavopivat ((Rac)-FT-4202) is an isomer of Etavopivat (HY-139573). Etavopivat is an orally active erythrocyte pyruvate kinase-R (PKR) activator that can be used in studies of sickle cell disease and other haemoglobinopathies .
    (<em>Rac</em>)-Etavopivat
  • HY-15448A

    (Rac)-VX-661

    CFTR Inflammation/Immunology
    (Rac)-Tezacaftor ((Rac)-VX-661) is a racemate of Tezacaftor (HY-15448). Tezacaftor is a F508del CFTR corrector. (Rac)-Tezacaftor can be used for the research of cystic fibrosis .
    (<em>Rac</em>)-Tezacaftor
  • HY-147260B

    (Rac)-SAGE-718

    TRP Channel Neurological Disease
    (Rac)-Dalzanemdor ((Rac)-SAGE-718) is an isomer of Dalzanemdor (HY-147260). Dalzanemdor is an orally active and highly intrinsically active N-methyl-d-aspartate receptor (NMDAR)-positive allosteric modulator (PAM). Dalzanemdor can be used in the research of Huntington's disease .
    (<em>Rac</em>)-Dalzanemdor
  • HY-12693A

    (Rac)-IAA-94

    Others Others
    (Rac)-Methylindazone ((Rac)-IAA-94) is the racemate of Methylindazone. Methylindazone is a potent CLIC1 channel blocker .
    (<em>Rac</em>)-Methylindazone
  • HY-10029A

    (Rac)-Rebemadlin

    MDM-2/p53 Autophagy Apoptosis E1/E2/E3 Enzyme Cancer
    (Rac)-Nutlin-3 (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). (Rac)-Nutlin-3 inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. (Rac)-Nutlin-3 has the potential for the study of TP53 wild-type ovarian carcinomas .
    (<em>Rac</em>)-Nutlin-3
  • HY-132809B

    (Rac)-CIN-107

    Others Endocrinology
    (Rac)-Baxdrostat is the isomer of Baxdrostat (HY-132809), and can be used as an experimental control. Baxdrostat is a aldosterone synthase inhibitor .
    (<em>Rac</em>)-Baxdrostat
  • HY-13749D

    (Rac)-MK-0431

    Autophagy Dipeptidyl Peptidase Metabolic Disease
    (Rac)-Sitagliptin is an isoform of Sitagliptin (HY-13749), which is a potent and orally active inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts .
    (<em>Rac</em>)-Sitagliptin
  • HY-107694

    (Rac)-MK-801

    Others Others
    (Rac)-Dizocilpine ((Rac)-MK-801) is the racemate of Dizocilpine (HY-15084B). Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist .
    (<em>Rac</em>)-Dizocilpine
  • HY-129179B

    (Rac)-APG-2575

    Bcl-2 Family Cancer
    (Rac)-Lisaftoclax ((Rac)-APG-2575) is a Bcl-2 inhibitor that can be uesd for hematologic malignancy research (CN112898295A) .
    (<em>Rac</em>)-Lisaftoclax
  • HY-W011303A

    (Rac)-4-Hydroxysphinganine

    Others Others
    (Rac)-Phytosphingosine ((Rac)-4-Hydroxysphinganine) is the racemate of Phytosphingosine (HY-W011303). Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC50 value of 33.4 μM and can be used in the study of type II diabetes .
    (<em>Rac</em>)-Phytosphingosine
  • HY-117962

    Guanylate Cyclase Metabolic Disease
    (Rac)-BI 703704 is a potent soluble guanylyl cyclase (sGC) activator. (Rac)-BI 703704 reduces progression of renal damage in the ZSF1 rat, and highlight the potential of sGC activation as an effective therapy for diabetic nephropathy .
    (<em>Rac</em>)-BI 703704
  • HY-112248

    Leukotriene Receptor Cardiovascular Disease Neurological Disease Inflammation/Immunology
    (Rac)-HAMI 3379 is the racemate of HAMI 3379. HAMI 3379 is a potent and selective Cysteinyl leukotriene (CysLT2) receptor antagonist .
    (<em>Rac</em>)-HAMI 3379
  • HY-108425B

    (Rac)-AMG8380

    Sodium Channel Neurological Disease
    (Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide antagonist of NaV1.7, with IC50s of 8.5 and 18.6 nM for hNaV1.7 and mNaV1.7, respectively .
    (<em>Rac</em>)-AMG8379
  • HY-136109B

    (Rac)-SEP-856

    5-HT Receptor Neurological Disease
    (Rac)-SEP-363856 is the racemate of SEP-363856. SEP-363856(SEP-856), an orally active and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 (SEP-856) has the potential for the treatment of schizophrenia .
    (<em>Rac</em>)-SEP-363856
  • HY-121604

    Calcium Channel Others
    (Rac)-MEM 1003 is the racemate of MEM 1003. MEM 1003, a dihydropyridine compound, is a potent L-type Ca 2+ channel antagonist and has the potential for Alzheimer’s disease research .
    (<em>Rac</em>)-MEM 1003
  • HY-111372A

    (Rac)-BAY 94-8862

    Mineralocorticoid Receptor Cardiovascular Disease
    (Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold) .
    (<em>Rac</em>)-Finerenone
  • HY-135653A

    (Rac)-BPN-19186

    Epoxide Hydrolase Neurological Disease
    (Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) .
    (<em>Rac</em>)-EC5026
  • HY-117884

    Apoptosis Cancer
    (Rac)-CCT 250863 (compound rac-21) is a selective and reversible NEK 2 inhibitor with an IC50 of 0.073 µM. (Rac)-CCT 250863 shows good effects of inducing cell cycle arrest and also can antiproliferative in cells (Pomalidomide sensitive/resistant). (Rac)-CCT 250863 induces apoptosis when combines with Pomalidomide .
    (<em>Rac</em>)-CCT 250863
  • HY-12168B

    (Rac)-BAY 12-9566

    MMP Cancer
    (Rac)-Tanomastat ((Rac)-BAY 12-9566) is the racemate of Tanomastat. Tanomastat (BAY 12-9566) is an orally bioavailable, non-peptidic biphenyl matrix metalloproteinases (MMPs) inhibitor with a Zn-binding carboxyl group. The Ki values are 11, 143, 301, and 1470 nM for MMP-2, MMP-3, MMP-9, MMP-13 respectively. Tanomastat shows anti-invasive and antimetastatic activity in several experimental tumor models .
    (<em>Rac</em>)-Tanomastat
  • HY-W127802

    (Rac)-(Bromoacetamidophenylmethyl)ethylenediaminetetraacetic acid

    Biochemical Assay Reagents Others
    (Rac)-EDTA-bromoacetamidophenylmethyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    (<em>Rac</em>)-EDTA-bromoacetamidophenylmethyl
  • HY-152943A

    (Rac)-EP-0035985

    Mitophagy Cancer
    (Rac)-MTK458 (compound 16) is an activator of mitophagy. EP-0035985 is the isomer of EP-0035985 .
    (<em>Rac</em>)-MTK458
  • HY-13245B

    (Rac)-INCB8761

    CCR Inflammation/Immunology
    (Rac)-PF-4136309 is an isoform of PF-4136309 (HY-13245), which is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
    (<em>Rac</em>)-PF-4136309
  • HY-16023B

    EM-343; (Rac)-EM-652

    Estrogen Receptor/ERR Cancer
    (Rac)-Acolbifene (EM-343; (Rac)-EM-652) is the racemic form of EM652 (estrogen receptor antagonist), has anti-estrogenic and estrogenic activities. (Rac)-Acolbifene (EM-343; (Rac)-EM-652) contains a piperidine ring, shows good pharmacological profile,relative binding affinity (RBA)=380 .
    (<em>Rac</em>)-Acolbifene
  • HY-107501

    (Rac)-1-Oleoyl-sn-glycero-3-phosphate sodium; (Rac)-1-Oleoyl-LPA sodium

    Others Neurological Disease
    (Rac)-1-Oleoyl lysophosphatidic acid ((Rac)-1-Oleoyl-sn-glycero-3-phosphate) sodium is the racemic isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614) .
    (<em>Rac</em>)-1-Oleoyl lysophosphatidic acid sodium
  • HY-111540A

    (Rac)-IDO1-IN-5

    Indoleamine 2,3-Dioxygenase (IDO) Cancer
    (Rac)-LY-3381916 ((Rac)-IDO1-IN-5; Example 1) is a racemate of LY-3381916 . LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1 .
    (<em>Rac</em>)-LY-3381916

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