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Results for "

(S)-(+)-Rolipram

" in MCE Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) HIV (1) Phosphodiesterase (PDE) (2)
By Research Areas:	Cancer (2) Inflammation/Immunology (1) Neurological Disease (2)

Cat. No.	Product Name	Target	Research Areas

(S)-(+)-Rolipram (+)-Rolipram; (S)-Rolipram	Phosphodiesterase (PDE) Apoptosis	Cancer Inflammation/Immunology Neurological Disease
(S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC₅₀ of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells.

*Rolipram* (R,S)-Rolipram; (±)-Rolipram; ZK 62711	Phosphodiesterase (PDE) Bacterial HIV	Neurological Disease Cancer
Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC₅₀s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.

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