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Results for "

11��-Hydroxysteroid Dehydrogenase Inhibitors

" in MCE Product Catalog:

315

Inhibitors & Agonists

1

Screening Libraries

2

Fluorescent Dye

27

Biochemical Assay Reagents

21

Peptides

44

Natural
Products

62

Recombinant Proteins

29

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Area
  • HY-P3820
    [Dehydro-Pro4] Substance P (4-11)

    		Peptides Inflammation/Immunology Neurological Disease
    [Dehydro-Pro4] Substance P (4-11) is a peptide fragment of Substance P. Substance P is a peptide mainly secreted by neurons. Substance P takes part in many biological processes, including nociception, inflammation and immunity.
  • HY-P3061
    [Hyp3]-Bradykinin

    		Bradykinin Receptor Endocrinology Cardiovascular Disease
    [Hyp3]-Bradykinin, naturally occurring peptide hormone, is a bradykinin receptor agonist. [Hyp3]-Bradykinin interacts with B2-bradykinin receptors and stimulates inositol phosphate production in cultured human fibroblasts.
  • HY-P3186
    Glucose dehydrogenase

    		Endogenous Metabolite Metabolic Disease
    Glucose dehydrogenase is a oxidoreductase. Glucose dehydrogenase catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP + to NADPH or, to a lesser extent, NAD + to NADH. Glucose dehydrogenase accepts both NAD + and NADP + as cofactors and can be used for the regeneration of NADH and NADPH.
  • HY-P2907
    Formate dehydrogenase

    		Endogenous Metabolite Others
    Formate dehydrogenase is an enzyme ubiquitous in prokaryotes and eukaryotes that catalyzes the reversible oxidation of formate to carbon dioxide. According to its metal content, structure and catalytic strategy, Formate dehydrogenase can be divided into two categories, non-metallic and metal-containing, which are often used in biochemical research.
  • HY-P3185
    β-Galactose dehydrogenase

    		Endogenous Metabolite Metabolic Disease
    β-Galactose dehydrogenase can make conversion of galactose to galactonolactone and the concomitant reduction of NAD to the fluorescent NADH. β-Galactose dehydrogenase can be used for the determination of galactose.
  • HY-P2993
    Isocitrate dehydrogenase

    ICDH

    		 Isocitrate Dehydrogenase (IDH) Metabolic Disease
    Isocitrate dehydrogenase (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P) + to NAD(P)H, it plays important roles in cellular metabolism.
  • HY-P2765
    Glycerol phosphate dehydrogenase

    GPDH

    		 Endogenous Metabolite Metabolic Disease
    Glycerol phosphate dehydrogenase catalyzes the conversion of dihydroxyacetone phosphate to α-glycerol phosphate.
  • HY-P2994
    3-Hydroxybutyrate dehydrogenase

    3-HBDH

    		 Endogenous Metabolite Others
    3-Hydroxybutyrate dehydrogenase (3-HBDH) is a mitochondrial enzyme, is often used in biochemical studies. 3-hydroxybutyrate dehydrogenase is involved in the synthesis and degradation of ketone bodies and butanoate metabolism. 3-Hydroxybutyrate dehydrogenase catalyzes (R)-3-hydroxybutanoate converts into acetoacetate.
  • HY-P2911
    Glutamate dehydrogenase (NAD(P))

    GLDH

    		 Mitochondrial Metabolism Others
    Glutamate dehydrogenase NAD(P) (GLDH) can be found in hepatocytes, renal tissue, brain, muscle, and intestinal cells. Glutamate dehydrogenase NAD(P) is often used in biochemical studies. Glutamate dehydrogenase is a mitochondrial enzyme, it catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-KG) as part of the urea cycle.
  • HY-P2809
    Malate dehydrogenase

    MDH

    		 Endogenous Metabolite Metabolic Disease
    Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes.
  • HY-P2804
    Glyceraldehyde phosphate dehydrogenase

    GADPH; G3PDH; GAPDH

    		 Peptides Others
    Glyceraldehyde phosphate dehydrogenase is the target of anti-thymocyte and anti-apoptotic agents. Glyceraldehyde phosphate dehydrogenase catalyzes the chain oxidation of reduced nicotinamide adenine dinucleotide by perhydroxyl radicals.
  • HY-P2897
    D-Lactate dehydrogenase

    D-LDH

    		 Lactate Dehydrogenase Others
    D-Lactate dehydrogenase (D-LDH) is an oxidoreductase that uses NAD + or NADP + as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research.
  • HY-P2740
    Alcohol dehydrogenase

    EC 1.1.1.1

    		 Endogenous Metabolite Metabolic Disease
    Alcohol dehydrogenase is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol.
  • HY-P2947
    Aldehyde dehydrogenase (NAD(P))

    ALDH

    		 Aldehyde Dehydrogenase (ALDH) Others
    Aldehyde dehydrogenase NAD(P) (ALDH) catalyzes the oxidation of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H, is often used in biochemical studies. The aldehyde dehydrogenases (ALDHs) are one of many enzyme systems the body utilizes to alleviate aldehyde stress.
  • HY-P2768
    Leucine dehydrogenase

    LDH, EC 1.4.1.9

    		 Endogenous Metabolite Metabolic Disease
    Leucine dehydrogenase can be purified from Bacillus spheroides. Leucine dehydrogenase catalyzed the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine, and the reductive amination of their keto analogues.
  • HY-P2901
    3α-Hydroxysteroid dehydrogenase

    3α-HSD

    		 Endogenous Metabolite Endocrinology
    3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism.
  • HY-P3124
    BIM-23190

    		Somatostatin Receptor Cancer
    BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly.
  • HY-P3124A
    BIM-23190 hydrochloride

    		Somatostatin Receptor Cancer
    BIM-23190 hydrochloride, a somatostatin analog, a selective SSRT2 and SSRT5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly.
  • HY-W105634
    Strombine

    		Peptides Others
    Strombine is a imino acid produced by a dehydrogenase. Strombine is a compound present in the hemolymph that is capable of cryoprotection.
  • HY-P4119
    Pep-1-Cysteamine

    		Peptides Others
    Pep-1-Cysteamine is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine has the ability to translocate across biological membranes and introduce active proteins inside cells.
  • HY-P3509
    PNC-28

    		Peptides Cancer
    PNC-28 is a peptide from the mdm-2-binding domain (residues 17–26) of the p53 protein which contains a membrane crossing-penetratin sequence. PNC-28 can be used for pancreatic cancer research.