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Targets Recommended: CRISPR/Cas9

Results for "1218779-75-9" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-13342
    Apatinib

    YN968D1

    VEGFR RET c-Kit Src Autophagy Cancer
    Apatinib (YN968D1) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 with an IC50 of 1 nM. Apatinib (YN968D1) also potently suppresses the activities of Ret, c-Kit and c-Src with IC50s of 13, 429 and 530 nM, respectively. Apatinib (YN968D1) inhibits cellular phosphorylation of VEGFR-2, c-kit and PDGFRβ.