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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-P9928

    REGN 727; SAR 236553

    Ser/Thr Protease Metabolic Disease
    Alirocumab (REGN 727) is a human monoclonal antibody inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9). Alirocumab specifically binds PCSK9, a down regulator of liver low-density lipoprotein (LDL)-receptors, thereby increasing the ability of the liver to bind LDL-cholesterol (LDL-C) and reducing levels of LDL-C in blood. Alirocumab can be used for the research of hypercholesterolemia.