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Results for "129425-81-6" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-136927

    STING Cancer Inflammation/Immunology
    MSA-2, a potent and orally available non-nucleotide STING agonist, has EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models.