1. Search Result

Search Result

Targets Recommended: NEDD8-activating Enzyme

Results for "1353644-70-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-104066


    EGFR Cancer
    Theliatinib (HMPL-309) is a potent, ATP-competitive, orally active and highly selective EGFR inhibitor with a Ki of 0.05 nM and an IC50 of 3 nM. Theliatinib has an IC50 of 22 nM for EGFR T790M/L858R mutant. Theliatinib shows >50-fold selectivity for EGFR than other kinases. Anti-tumor activity.