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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "1358488-78-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-115497

    E1/E2/E3 Enzyme Inflammation/Immunology
    BRD5529 is a selective CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction inhibitor with an IC50 of 8.6 μM. BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation and activation of CARD9, and demonstrates cellular activity and selectivity in CARD9-dependent pathways.