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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "147059-75-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-103399
    Trovafloxacin mesylate

    Bacterial Topoisomerase Infection
    Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1.