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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "1494684-28-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-123938

    PI3K Cancer
    CYH33 is an orally active, highly selective PI3Kα inhibitor with IC50s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ isoform, respectively. CYH33 inhibits phosphorylation of Akt, ERK and induces significant G1 phase arrest in breast cancer cells and non-small cell lung cancer (NSCLC) cells. CYH33 has potent activity against solid tumors.