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Results for "

1603845-32-4

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-100848
    TX1-85-1

    		EGFR Cancer
    TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling.