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Targets Recommended: CRISPR/Cas9

Results for "1609392-27-9" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-117287
    BMS-986165

    JAK Interleukin Related Inflammation/Immunology
    BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. BMS-986165 inhibits IL-12/23 and type I IFN pathways.