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Results for "

162359-56-0

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-12005
    Fingolimod hydrochloride
    20+ Cited Publications

    FTY720

    		 LPL Receptor PAK Inflammation/Immunology Cancer
    Fingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1-phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator.
  • HY-11063
    Fingolimod
    20+ Cited Publications

    FTY720 free base

    		 LPL Receptor PAK Cancer Inflammation/Immunology
    Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.