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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter
Results for "


" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-114338


    CDK Cancer
    Dalpiciclib (SHR-6390) is a highly selective, orally bioavailable CDK4/6 inhibitor with comparable potencies against CDK4 (IC50=12.4 nM) and CDK6 (IC50=9.9 nM). Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor-suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.