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Targets Recommended: NEDD8-activating Enzyme

Results for "1643120-60-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-114413

    HSP Apoptosis Cancer
    YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration.