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Targets Recommended: NEDD8-activating Enzyme

Results for "177943-33-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-116451
    PF-04859989 hydrochloride

    Others Neurological Disease
    PF-04859989 hydrochloride is a brain-penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC50s of 23 and 263 nM for hKAT II and rKAT II. PF-04859989 hydrochloride is selective for KAT II over human KAT I, KAT III, and KAT IV (IC50s of 22, 11, and >50 μM, respectively).