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Results for "179237-49-1" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-108263
    3-Hydroxy Midostaurin


    FLT3 Cancer
    3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412.