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Results for "

17β-HSD

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

3

Natural
Products

1

Recombinant Proteins

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145433
    17β-HSD1-IN-1

    		Others Cancer
    17β-HSD1-IN-1 (Compound 1) is a highly selective 17β-HSD1 inhibitor with IC50s of 5.6 and 3155 nM for 17β-HSD1 and 17β-HSD2, respectively. 17β-HSD1-IN-1 can be used for the research of non-small cell lung cancer (NSCLC) .
    <em>17β-HSD</em>1-IN-1
  • HY-155534
    17β-HSD10-IN-1

    		Endogenous Metabolite Others
    17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects .
    <em>17β-HSD</em>10-IN-1
  • HY-157935
    17β-HSD10-IN-3

    		Endogenous Metabolite Neurological Disease
    17β-HSD10-IN-3 (compound 23) is a 17β-HSD10 inhibitor with the IC50 of 5.59 μM. 17β-HSD10-IN-3 shows no cell cytotoxicity toward the HEK-293 cell line up to 20 μM .
    <em>17β-HSD</em>10-IN-3
  • HY-155535
    17β-HSD10-IN-2

    		Endogenous Metabolite Neurological Disease
    17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer .
    <em>17β-HSD</em>10-IN-2
  • HY-155010
    Steroid sulfatase/17β-HSD1-IN-5

    		Steroid Sulfatase Metabolic Disease
    Steroid sulfatase/17β-HSD1-IN-5 is a irreversible inhibitor of steroid sulfatase (STS) .Steroid sulfatase/17β-HSD1-IN-5 is a reversible and selective inhibitor of 7β-hydroxysteroid dehydrogenase type1 (17β-HSD1), with IC50s of 43 nM and 6.2μM for 17β-HSD1 and 17β-HSD2, respectively. Steroid sulfatase/17β-HSD1-IN-5 can be used for metabolic disease (especially for endometriosis) research .
    Steroid sulfatase/<em>17β-HSD</em>1-IN-5
  • HY-151201
    Steroid sulfatase/17β-HSD1-IN-3

    		Steroid Sulfatase Cancer
    Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 irreversibly inhibits hSTS activity with anIC50 value of 27 nM. Steroid sulfatase/17β-HSD1-IN-3 can be used in the study of endometriosis and other estrogen-dependent diseases .
    Steroid sulfatase/<em>17β-HSD</em>1-IN-3
  • HY-151202
    Steroid sulfatase/17β-HSD1-IN-4

    		Steroid Sulfatase Cancer
    Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS activity with anIC50 value of 63 nM. Steroid sulfatase/17β-HSD1-IN-4 can be used in the study of endometriosis and other estrogen-dependent diseases .
    Steroid sulfatase/<em>17β-HSD</em>1-IN-4
  • HY-151199
    Steroid sulfatase/17β-HSD1-IN-1

    		Steroid Sulfatase Endocrinology Cancer
    Steroid sulfatase/17β-HSD1-IN-1 is a potent steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor with an IC50 value of 28 nM for cellular human steroid sulfatase. Steroid sulfatase/17β-HSD1-IN-1 can be used to research estrogen-dependent diseases .
    Steroid sulfatase/<em>17β-HSD</em>1-IN-1
  • HY-103394
    TC HSD 21

    		Others Cancer
    TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors .
    TC HSD 21
  • HY-W016604
    4'-Hydroxyvalerophenone

    4-Pentanoylphenol; 4-Valerylphenol

    		 17β-HSD Cancer
    4'-Hydroxyvalerophenone (Compound 4) is an inhibitor of 17β-hydroxysteroid dehydrogenase (17β-HSD) with an IC50 of 60.52 μM .
    4'-Hydroxyvalerophenone
  • HY-N9551
    Eriodictyol chalcone

    		Cytochrome P450 Metabolic Disease
    Eriodictyol chalcone possesses both anti-aromatase and an anti-17β-HSD activity .
    Eriodictyol chalcone
  • HY-118382
    SCH-451659

    		17β-HSD Cancer
    SCH-451659 is an inhibitor of 17β-hydroxysteroid dehydrogenases (17β-HSDs) for cancer research .
    SCH-451659
  • HY-18173
    AZD8329

    		11β-HSD Metabolic Disease
    AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3 .
    AZD8329
  • HY-B1643
    Ethyl Vanillate

    		Fungal Infection
    Ethyl Vanillate is a fungicidal agent. Ethyl Vanillate inhibits 17β-HSD2 with an IC50 1.3 µM .
    Ethyl Vanillate
  • HY-160618
    11β-HSD2-IN-2

    		11β-HSD Metabolic Disease
    11β-HSD2-IN-2 (compound 3) is a selective inhibitor for 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) with an IC50 of 300 nM .
    11β-HSD2-IN-2

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