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Results for "18000-24-3" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-100811
    7-Chloro-4-hydroxyquinoline-2-carboxylic acid

    7-Chlorokynurenic acid

    iGluR Neurological Disease
    7-Chloro-4-hydroxyquinoline-2-carboxylic acid (7-Chlorokynurenic acid) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chloro-4-hydroxyquinoline-2-carboxylic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chloro-4-hydroxyquinoline-2-carboxylic acid has potent antinociceptive actions after neuraxial delivery.