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Targets Recommended: NEDD8-activating Enzyme

Results for "1818291-27-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-100765

    MDM-2/p53 Cancer
    BI-0252 is an orally active, selective MDM2-p53 inhibitor with an IC50 of 4 nM. BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.