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Results for "2098191-54-7" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-112163A


    Eukaryotic Initiation Factor (eIF) SARS-CoV Apoptosis Cancer Infection
    rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex.