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Results for "2101938-42-3" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-134581
    Enpatoran

    M5049

    Toll-like Receptor (TLR) Inflammation/Immunology
    Enpatoran (M5049) is an orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran can block both innate and adaptive autoimmunity. Enpatoran is inactive against TLR3, TLR4 and TLR9. Enpatoran (M5049) can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran (M5049) inhibits cytokine release, causing great potency in pharmacokinetic/pharmacodynamic properties.