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Targets Recommended: NEDD8-activating Enzyme

Results for "2114339-57-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-133017

    Estrogen Receptor/ERR Cancer
    SAR439859 (compound 43d) is an orally active, nonsteroidal and selective estrogen receptor degrader (SERD). SAR439859 is a potent ER antagonist and has ER degrading activity with an EC50 of 0.2 nM for ERα degradation. SAR439859 demonstrates robust antitumor efficacy and limited cross-resistance in ER + breast cancer.