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Results for "2121-12-2" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-N1971

    Topoisomerase Caspase Ferroptosis Autophagy Cancer
    Ungeremine, a phenanthridine type alkaloid, is extracted of the bulbs of Pancratium Illyricum. Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. Ungeremine displays cytotoxic activity towards the 9 cancer cell lines, including drug-sensitive and MDR phenotypes. Ungeremine induced ferroptosis, necroptosis, autophagy as well as apoptosis mediated by caspase activation, MMP alteration and increase ROS production.