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Targets Recommended: NEDD8-activating Enzyme

Results for "2134169-43-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-136360

    Epigenetic Reader Domain Cancer
    MI-3454 is an orally active, highly potent and selective menin-MLL1 interaction inhibitor with an IC50 of 0.51 nM. MI-3454 inhibits proliferation, induces differentiation and complete remission or regression of leukemia in mouse models of MLL1-rearranged or NPM1-mutated leukemia through downregulation of key genes involved in leukemogenesis.