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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "2160546-07-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-137092

    Phosphatase Cancer
    IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. IACS-13909 is more selective for SHP2 than other phosphatases (including SHP1). IACS-13909 has antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinases (RTK)-dependent cancers.