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Targets Recommended: p38 MAPK

Results for "2163793-38-0" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-125877
    Mcl1-IN-14

    PROTAC Bcl-2 Family Cancer
    Mcl1-IN-14 (compound C3), a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM. Mcl1-IN-14 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity.