1. Search Result

Search Result

Targets Recommended: PI4K FXR Oct3/4 MAP4K Serotonin Transporter

Results for "2168525-92-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-136242

    Androgen Receptor Cancer Endocrinology
    UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively. UT-34 binds to ligand-binding domain (LBD) and function-1 (AF-1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT-34 has anti-prostate cancer efficacy.