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Results for "

2230821-27-7

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-123921
    Gefitinib-based PROTAC 3

    		PROTACs EGFR Cancer
    Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively.