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Targets Recommended: NEDD8-activating Enzyme

Results for "2230854-93-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-137466

    Topoisomerase Cancer
    ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etoposide (IC50=120 μM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research.