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Results for "

2247061-09-0

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-145733
    DI-1859

    E1/E2/E3 Enzyme Cardiovascular Disease
    DI-1859 is a potent, selective and covalent inhibitor of DCN1. DI-1859 inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 induces a robust increase of NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver damage.