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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "2250025-94-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-136258
    nAChR agonist CMPI hydrochloride

    nAChR Neurological Disease
    nAChR agonist CMPI hydrochloride is a potent and selective positive allosteric modulator (PAM) of nAChR containing a α4:α4 subunit interface. nAChR agonist CMPI hydrochloride enhances the response of (α4)3(β2)2 nAChR to ACh (10 µM) with an EC50 of 0.26 µM. nAChR agonist CMPI hydrochloride has potential for the research of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity.