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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "2253744-54-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-126010

    Others Cardiovascular Disease
    Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca 2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta.