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Targets Recommended: NEDD8-activating Enzyme

Results for "2369979-68-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-131881

    mAChR Neurological Disease
    JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [ 3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.