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2413986-35-1

" in MCE Product Catalog:
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Cat. No. Product Name Target Research Areas
  • HY-133552
    RORγt Inverse agonist 10

    		ROR Inflammation/Immunology
    RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R