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Results for "2414572-47-5" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-136789
    BDTX-189

    EGFR Cancer
    BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, includes EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity.