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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "2419160-96-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-138671
    DprE1-IN-4

    Bacterial Infection
    DprE1-IN-4 is a potent and orally active noncovalent DprE1 inhibitor with an IC50 of 0.90 μg/mL. DprE1-IN-4 exhibits potent in vitro activity against M. tuberculosis H37Rv and drug-resistant tuberculosis strain with MIC values of 0.12 μg/mL and 0.24 μg/mL, respectively. DprE1-IN-4 displays acceptable pharmacokinetic property and shows significant bactericidal activity in an acute mouse model of tuberculosis.