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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-137206

    Others Cancer
    ALV2 is a potent and selective Helios degrader. ALV2 binds CRBN, with an IC50 of 0.57 μM. Helios is the zinc-finger transcription factor that can maintain a stable Treg cell phenotype in the inflammatory tumor microenvironment.