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Targets Recommended: NEDD8-activating Enzyme

Results for "24418-86-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-12895
    SKI V

    SPHK PI3K Apoptosis Cancer
    SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity.