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Results for "2519823-34-6" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-139039
    BSJ-4-116

    PROTAC CDK Cancer
    BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. BSJ-4-116 downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation). BSJ-4-116 exhibits potent antiproliferative effects, alone and in combination with the poly(ADP-ribose) polymerase inhibitor Olaparib (HY-10162).