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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-101064

    N-FMOC-leucine; NPC 15199; NSC 334290

    PPAR Metabolic Disease
    Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity.