1. Search Result
Search Result
Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter
Results for "

357425-68-4

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-138879B
    CP-601932

    (1S,5R)-CP-601927

    nAChR Neurological Disease
    CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21 nM; EC50=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS.