Search Result
Results for "
4 hydroxy tempo Inhibitors
" in MedChemExpress (MCE) Product Catalog:
1203
Inhibitors & Agonists
62
Biochemical Assay Reagents
251
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W001187
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Mitochondrial Metabolism
DNA/RNA Synthesis
Reactive Oxygen Species
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Cancer
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Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells .
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- HY-112879
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- HY-W008216
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hydroxy Dimetridazole
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Drug Metabolite
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Others
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HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections .
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- HY-151847
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ADC Linker
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Others
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N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-W002004
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4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl
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Biochemical Assay Reagents
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Others
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4-Amino-TEMPO can be used as a spin label for detecting radicals and the damage caused by them. 4-Amino-TEMPO possesses superoxide dismutase-mimetic activity, enabling it to easily penetrate cells and protect them from oxidative damage induced by H2O2. Additionally, 4-Amino-TEMPO exhibits significant radiation protective properties, effectively safeguarding DNA from oxidative stress-induced damage caused by UV exposure due to its ability to maintain a positive charge. Furthermore, 4-Amino-TEMPO is a highly selective oxidation catalyst widely used in the research and development of various specialty chemicals, including fragrances, pesticides, and others .
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- HY-W001187S
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DNA/RNA Synthesis
Mitochondrial Metabolism
Reactive Oxygen Species
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Cancer
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Tempo-d18 is the deuterium labeled Tempo[1]. Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects[2][3][4][5].
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- HY-W001187R
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Mitochondrial Metabolism
DNA/RNA Synthesis
Reactive Oxygen Species
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Cancer
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Tempo (Standard) is the analytical standard of Tempo. This product is intended for research and analytical applications. Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells [4].
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- HY-140512
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PROTAC Linkers
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Cancer
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Acid-PEG5-TEMPO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W777072
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HIV
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Others
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4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA. It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.
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- HY-W008216S
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hydroxy Dimetridazole-d3
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Drug Metabolite
Isotope-Labeled Compounds
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Infection
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HMMNI-d3 is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].
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- HY-129242
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4-Oxo-tempo
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SOD
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Others
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Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure .
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- HY-100561
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- HY-130319
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- HY-158104
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ATF6
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Others
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LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
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- HY-P3100
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Parasite
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Infection
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Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
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- HY-W008216R
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Drug Metabolite
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Others
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HMMNI (Standard) is the analytical standard of HMMNI. This product is intended for research and analytical applications. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections .
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- HY-145461
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5-hydroxy lenalidomide
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Others
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Others
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Hydroxy lenalidomide (5-Hydroxy lenalidomide) is a metabolite of lenalidomide that is present as a minor component in plasma and excreta, accounting for less than 5% of the total radioactivity, following oral administration of lenalidomide in healthy male subjects.
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- HY-164746
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Drug Metabolite
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Metabolic Disease
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4′-Hydroxy Nitazene is the universal metabolite of the nitazene analogs. 4′-Hydroxy Nitazene is a metabolite of isotonitazene .
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- HY-Y0026
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3-hydroxy-4-methylbenzoic acid
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Biochemical Assay Reagents
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Others
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3-Hydroxy-4-methylbenzoic acid (3-Hydroxy-4-methylbenzoic acid) is a biological material or organic compound that can be used in life science research .
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- HY-115354
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Drug Metabolite
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Neurological Disease
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4-Hydroxy alprazolam is a metabolite of Alprazolam. Alprazolam is metabolized primarily by hepatic microsomal oxidation, yielding 4-Hydroxy alprazolam .
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- HY-124245R
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Others
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Others
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3-Hydroxy desloratadine (Standard) is the analytical standard of 3-Hydroxy desloratadine. This product is intended for research and analytical applications. 3-Hydroxy desloratidine is a metabolite of Desloratidine .
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- HY-N9012
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Others
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Others
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2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde is a Phenols product that can be isolated from the roots of Dalbergia congesta .
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- HY-114649
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- HY-15550R
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Drug Metabolite
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Neurological Disease
Inflammation/Immunology
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4'-Hydroxy diclofenac (Standard) is the analytical standard of 4'-Hydroxy diclofenac. This product is intended for research and analytical applications. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties .
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- HY-124245S2
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Isotope-Labeled Compounds
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Others
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3-Hydroxy desloratadine-d6 is deuterated labeled 3-Hydroxy desloratadine (HY-124245). 3-Hydroxy desloratidine is a metabolite of Desloratidine .
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- HY-N9241
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Others
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Neurological Disease
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3-Hydroxy-7-methoxyflavone (compound 1) is a
flavonoid. 3-Hydroxy-7-methoxyflavone is isolated from natural Salvia
elegans. 3-Hydroxy-7-methoxyflavone has anti-anxiety effect
.
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- HY-133111
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5-HT Receptor
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Neurological Disease
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3-Hydroxy agomelatine is a metabolite of Agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM .
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- HY-W740630
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5-HT Receptor
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Neurological Disease
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8-Hydroxy mirtazapine is a metabolite of the antidepressant Mirtazapine (HY-B0352). 8-Hydroxy mirtazapine is formed from mMirtazapine by the cytochrome P450 (CYP) isoform CYP2D6.
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- HY-N9224
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Others
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Others
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5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a Phenols product that can be isolated from the herbs of Artemisia dracunculus. .
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- HY-124245
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Others
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Others
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3-Hydroxy desloratidine is a metabolite of Desloratidine .
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- HY-170039
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- HY-116688
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Others
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Others
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2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy acid dehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease .
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- HY-118133
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Drug Metabolite
COX
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Inflammation/Immunology
Cancer
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4'-Hydroxy flurbiprofen is an oxidative metabolite of Flurbiprofen (HY-10582) via the cytochrome P450 enzyme system. 4'-Hydroxy flurbiprofen inhibits COX-1 by 94% at a concentration of 1000 µM .
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- HY-122303
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5-HT Receptor
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Neurological Disease
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4-hydroxy DiPT (hydrochloride) is an 5-HT2A agonist that induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential. 4-hydroxy DiPT (hydrochloride) is promising for research of hallucinogen .
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- HY-135335S
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Drug Metabolite
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Metabolic Disease
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3'-Hydroxy Repaglinide-d5 is the deuterium labeled 3'-Hydroxy Repaglinide. 3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide[1].
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- HY-143976S
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- HY-143367S
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- HY-W818693
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Others
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Cancer
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3-Hydroxy-3-phenylpentanamide is a compound with neuroprotective activity. 3-Hydroxy-3-phenylpentanamide shows protective effects against ischemic brain injury and cerebral hemorrhage. 3-Hydroxy-3-phenylpentanamide is studied in psychiatry as a potential anxiety, depression and addiction suppressant compound. 3-Hydroxy-3-phenylpentanamide shows antitumor activity in oncology, acting by inducing apoptosis and inhibiting tumor growth. 3-Hydroxy-3-phenylpentanamide also has protective effects against epileptic seizures .
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- HY-144950S
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Isotope-Labeled Compounds
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Others
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3-Hydroxy benzopyrene-d11 is the deuterium labeled 3-Hydroxy benzopyrene (HY-144950) . 3-Hydroxy benzopyrene is a metabolite of Benzopyrene (HY-107377) .
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- HY-G0003
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P88; hydroxy Iloperidone
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Drug Metabolite
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Others
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Iloperidone metabolite Hydroxy Iloperidone (P88; Hydroxy Iloperidone) is a metabolite of Iloperidone, which is an atypical antipsychotic.
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- HY-N2674
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5-hydroxy-1-methoxyxanthen-9-one
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Others
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Others
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5-Hydroxy-1-methoxyxanthone (5-Hydroxy-1-methoxyxanthen-9-one) is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .
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- HY-W016221R
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Drug Metabolite
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Inflammation/Immunology
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6-Hydroxy Chlorzoxazone (Standard) is the analytical standard of 6-Hydroxy Chlorzoxazone. This product is intended for research and analytical applications. 6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort .
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- HY-135212R
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Endogenous Metabolite
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Metabolic Disease
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Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-N5033
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Others
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Cancer
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17-Hydroxy sprengerinin C (compound 10) is a glycoside compound isolated from rhizomes of Polygonatum sibiricum. 17-Hydroxy sprengerinin C possesses stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increases the production of Bax .
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- HY-126121R
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COX
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Inflammation/Immunology
Cancer
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2-Hydroxy Ibuprofen (Standard) is the analytical standard of 2-Hydroxy Ibuprofen. This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
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- HY-132490S
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- HY-12389S
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- HY-132423S
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- HY-132483S
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- HY-132372S
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- HY-132425S
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- HY-141696S
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- HY-124245S
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- HY-132427S
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- HY-132329S
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- HY-132439S
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- HY-132370S
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- HY-132461S
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- HY-132436S
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- HY-124355S
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- HY-132461S1
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- HY-143958S
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- HY-143972S
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- HY-143981S
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- HY-144155S
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- HY-144156S
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- HY-143772S
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- HY-143773S
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- HY-15550
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- HY-126121S
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(±)-2-hydroxy Ibuprofen-d6
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Isotope-Labeled Compounds
COX
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Inflammation/Immunology
Cancer
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2-Hydroxy Ibuprofen-d6 is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].
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- HY-W010254
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Parasite
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Infection
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4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM .
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- HY-132484S
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- HY-132330S1
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- HY-122277S
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- HY-15550S
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Drug Metabolite
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Neurological Disease
Inflammation/Immunology
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4'-Hydroxy diclofenac-d4 is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[1][2].
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- HY-171028
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- HY-137414
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20-hydroxy-PGE2
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Drug Metabolite
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Endocrinology
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20-Hydroxy Prostaglandin E2 (20-Hydroxy-PGE2) is a metabolite of Prostaglandin E2 (HY-101952) that can be metabolized by cytochrome P450 .
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- HY-137547
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Prostaglandin Receptor
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Metabolic Disease
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20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
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- HY-W740784S
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- HY-N13284
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Fungal
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Infection
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13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that has anti-fungal activity .
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- HY-N8047
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Others
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Others
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5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone is a Phenols product that can be isolated from the rhizomes of Curcuma longa L. .
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- HY-116441
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Drug Metabolite
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Neurological Disease
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4-Hydroxy-3-methoxyamphetamine hydrochloride is a metabolite of 3,4-Methylenedioxymethamphetamine (MDMA). 4-Hydroxy-3-methoxyamphetamine hydrochloride can be used for forensic analysis .
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- HY-N7602
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Others
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Others
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10-Hydroxy majoroside is a methanol extract isolated from plantago asiatica .
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- HY-169463
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- HY-133111S
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5-HT Receptor
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Neurological Disease
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3-Hydroxy agomelatine-d3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM[1].
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- HY-N0445
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Tyrosinase
Bacterial
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Cancer
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2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor . 2-Hydroxy-4-methoxybenzaldehyde, an isomer of Vanillin, could be used to synthesis Urolithin M7
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- HY-128828
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Drug Metabolite
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Metabolic Disease
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2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.
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- HY-W001663
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Bacterial
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Infection
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4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .
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- HY-149504
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Drug Metabolite
mAChR
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Neurological Disease
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3-Hydroxy darifenacin is a metabolite of Darifenacin (HY-A0033). 3-Hydroxy darifenacin is an antagonist of M1-5 muscarinic receptors with Kis values of 17.78, 79.43, 2.24, 36.31 and 6.17 nM, respectively in CHO cells .
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- HY-164998
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- HY-N8797
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Others
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Infection
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Methyl 1-hydroxy-4-oxocyclohexaneacetate (Compound
7) is a lactone. Methyl 1-hydroxy-4-oxocyclohexaneacetate is isolated from the
natural Senecio scandens. Methyl
1-hydroxy-4-oxocyclohexaneacetate has anti-inflammatory andantibacterialactivity .
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- HY-12772
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Itraconazole metabolite hydroxy Itraconazole; R-63373
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Fungal
Drug Metabolite
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Others
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Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
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- HY-12773AS1
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- HY-155842S
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- HY-W698964
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Biochemical Assay Reagents
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Metabolic Disease
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2′-Hydroxy-5′-nitrohexadecanamide is a lysosomal hydrolase inhibitor and is a lipid containing pentadecanoic acid and a terminal nitrophenol in its structure. 2′-Hydroxy-5′-nitrohexadecanamide can cause intracellular lipid accumulation by inhibiting lysosomal hydrolase activity. Additionally, 2′-Hydroxy-5′-nitrohexadecanamide can be used to synthesize chromogenic substrates for measuring sphingolipase activity .
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- HY-135212S
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Endogenous Metabolite
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Metabolic Disease
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Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].
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- HY-126121
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(±)-2-hydroxy Ibuprofen
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COX
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Inflammation/Immunology
Cancer
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2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
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- HY-115411
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NO Synthase
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Others
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L-Hydroxy arginine acetate is an intermediate in the catabolism of L-arginine. L-Hydroxy arginine acetate is a substrate for NO synthase .
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- HY-126852S
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- HY-141987S1
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- HY-N7971
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Endogenous Metabolite
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Cardiovascular Disease
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2-Hydroxy-1-Methoxyaporphine is an alkaloid that can be isolated from Nelumbo nucifera. 2-Hydroxy-1-Methoxyaporphine is the major active ingredient of the Chinese traditional medicine Jiang-Zhi-Ning .
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- HY-135212
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Endogenous Metabolite
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Metabolic Disease
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Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-118796
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4-HO-MET; 4-hydroxy-N-methyl-N-ethyltryptamine
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5-HT Receptor
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Neurological Disease
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4-Hydroxy MET (4-HO-MET) is a psychoactive tryptamine (NPS), a structural variant of the endogenous neurotransmitter serotonin. 4-Hydroxy MET has hallucinogenic effects, affecting mood, movement, and cognitive function .
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- HY-144155S1
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- HY-170004S
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- HY-W016103
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- HY-23195
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- HY-W007888
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- HY-W008188
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- HY-N7608
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- HY-N1731
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2-hydroxy-5-methoxyacetophenone
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Biochemical Assay Reagents
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Others
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2′-Hydroxy-5′-methoxyacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-122277
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- HY-15328
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- HY-W011340S
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- HY-132352S1
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- HY-143816S
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- HY-143918S
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- HY-143928S
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- HY-124245S1
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- HY-143840S
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- HY-N13543
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Others
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Others
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5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one is a natural product .
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- HY-W703869
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N-Methylserotonin oxalate; 5-hydroxy-N-methyl tryptamine oxalate
|
Drug Metabolite
|
Neurological Disease
|
|
5-Hydroxy NMT (N-Methylserotonin) oxalate is a metabolite of 5-HT and belongs to the tryptamine class of compounds. Elevated levels of 5-Hydroxy NMT oxalate in plasma are associated with cocaine addiction .
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-
- HY-15550S1
-
|
|
Drug Metabolite
|
Inflammation/Immunology
|
|
4'-Hydroxy diclofenac- 13C6 is the 13C labeled 4'-Hydroxy diclofenac[1]. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[2][3].
|
-
- HY-W011340R
-
|
|
Endogenous Metabolite
|
Inflammation/Immunology
|
|
5-Hydroxy flunixin (Standard) is the analytical standard of 5-Hydroxy flunixin. This product is intended for research and analytical applications. 5-Hydroxy flunixin, the principal metabolite of Flunixin (HY-121046), retains the Flunixin's anti-inflammatory properties and plays a significant role in mitigating pain and inflammation in various veterinary applications. It assists in alleviating conditions such as colic in horses, musculoskeletal disorders, and infectious diseases in cattle, while also supporting the management of mastitis-metritis-agalactia syndrome in sows.
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-
- HY-75625
-
|
4-Methoxysalicylic Acid
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Others
|
Others
|
|
2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.
|
-
- HY-142641S
-
-
- HY-N3505
-
|
|
Others
|
Others
|
|
14-Hydroxy sprengerinin C is a steroidal compound found in Ophiopogon japonicus.
|
-
- HY-N13416
-
|
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Others
|
Others
|
|
6-Hydroxy-7-methoxydihydroligustilide is a natural product .
|
-
- HY-138545
-
|
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Others
|
Others
|
|
4-Hydroxy-6-methylcoumarin is a Coumarin product .
|
-
- HY-168321
-
-
- HY-129254
-
-
- HY-W702712
-
-
- HY-123672S
-
-
- HY-107043
-
-
- HY-165909
-
-
- HY-132477S
-
-
- HY-A0019BS
-
-
- HY-123672R
-
|
|
HMG-CoA Reductase (HMGCR)
|
Metabolic Disease
|
|
Lovastatin hydroxy acid (sodium) (Standard) is the analytical standard of Lovastatin hydroxy acid (sodium). This product is intended for research and analytical applications. Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM .
|
-
- HY-132394S
-
-
- HY-132466S
-
-
- HY-122508S
-
-
- HY-N8142
-
|
|
Others
|
Others
|
|
6-Hydroxy-2-phenethylchromone possesses antioxidant activity .
|
-
- HY-144228S
-
-
- HY-146477S
-
-
- HY-165844
-
-
- HY-147064
-
|
|
Others
|
Others
|
|
DL-4-Hydroxy-2-ketoglutarate lithium is the substrate of 4-hydroxy-2-oxoglutarate aldolase (HOGA). DL-4-Hydroxy-2-ketoglutarate lithium can be cleaved by HOGA to produce pyruvate and glyoxylate .
|
-
- HY-W002484R
-
|
|
Others
|
Inflammation/Immunology
|
|
3-Hydroxy-4-methoxyacetophenone (Standard) is the analytical standard of 3-Hydroxy-4-methoxyacetophenone. This product is intended for research and analytical applications. 3-Hydroxy-4-methoxyacetophenone(Acetoisovanillone; Isoacetovanillone) is an active compound isolated from P. spinosa. Isoacetovanillone possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon .
|
-
- HY-168322
-
|
|
Fluorescent Dye
|
Others
|
|
2-Hydroxy nile red trifluoromethanesulfonate is a fluorescent probe, that enters into oligodeoxyribonucleic acid as a nucleotide replacement. 2-Hydroxy nile red trifluoromethanesulfonate can be used as a DNA probe for detecting the polar changes in tumor microenvironments .
|
-
- HY-139067
-
|
|
LXR
|
Cardiovascular Disease
|
|
25(S)-27-Hydroxy cholesterol is a metabolite of CYP27A1 mediated cholesterol hydroxylation. 25(S)-27-Hydroxy cholesterol inhibits melanoma cell proliferation .
|
-
- HY-W004681S
-
-
- HY-144228S1
-
-
- HY-W742358
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
4'-Hydroxy pyrimethanil-d4 is the deuterium labeled 4'-Hydroxy pyrimethanil. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
-
- HY-121758
-
-
- HY-155587
-
|
|
Others
|
Cancer
|
|
Hydroxy-PP is a potent CBR1 inhibitor with an IC50 value of 0.78 μM. Hydroxy-PP also potently inhibits the cytoplasmic tyrosine kinase Fyn with an IC50 value of 5 nM .
|
-
- HY-127025
-
|
|
Endogenous Metabolite
|
Others
|
|
8-Hydroxy loxapine is the relatively inactive oxidative metabolite of Loxapine (HY-17390), compared to 7-OH-loxapine .
|
-
- HY-W036733
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Hydroxy-4-methylcyclohexanone is a useful synthetic reagent extracted from patent JP2009022162A. 4-Hydroxy-4-methylcyclohexanone can be used to synthesize trans-4-amino-1-methylcyclohexanol which is intermediate of pharmaceutical synthesis .
|
-
- HY-W777188
-
-
- HY-126044
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors .
|
-
- HY-W048312
-
-
- HY-131422S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
rac 8-Hydroxy Efavirenz-d4 is the deuterium labeled rac 8-Hydroxy Efavirenz[1]. rac 8-Hydroxy Efavirenz-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-22167
-
|
|
Others
|
Others
|
|
Methyl 2-hydroxy-4-methylvalerate is one of dominant volatile compounds in Zhenjiang aromatic vinegar. Methyl 2-hydroxy-4-methylvalerate is used for charting flavour biosynthesis networks of vinegar microbiota .
|
-
- HY-137310
-
|
|
HMG-CoA Reductase (HMGCR)
Drug Metabolite
|
Metabolic Disease
|
|
4-Hydroxy atorvastatin hemicalcium is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin .
|
-
- HY-W025101S
-
|
Ethyl 3-hydroxy-3-methylbutyrate-d6
|
Isotope-Labeled Compounds
|
Others
|
|
Ethyl 3-hydroxy-3-methylbutanoate-d6 is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].
|
-
- HY-165760
-
-
- HY-165772
-
-
- HY-165908
-
-
- HY-W707624
-
-
- HY-139965S
-
-
- HY-143017S
-
-
- HY-N8680
-
|
|
Others
|
Inflammation/Immunology
|
|
12-Hydroxy-2,3-dihydroeuparin (compound 7) is a natural product that can be isolated from the aerial parts of Ophryosporus axilliflorus. 12-Hydroxy-2,3-dihydroeuparin shows extremely anti-inflammatory activity .
|
-
- HY-100561S1
-
|
4-hydroxy-tempo-d17
|
Autophagy
Reactive Oxygen Species
|
Cancer
|
|
Tempol-d17 is the deuterium labeled Tempol[1]. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS)[2][3].
|
-
- HY-142125S1
-
-
- HY-168794
-
-
- HY-168795
-
-
- HY-W011540S
-
|
|
Endogenous Metabolite
|
Cancer
|
|
8-Hydroxy-2'-deoxyguanosine- 15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine[1]. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[2].
|
-
- HY-149503
-
-
- HY-139433
-
-
- HY-136346S
-
|
|
Drug Metabolite
|
Cardiovascular Disease
|
|
Ortho-hydroxy atorvastatin lactone-d5 is deuterium labeled 2-Hydroxy atorvastatin lactone. 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].
|
-
- HY-76105
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
D-Proline, 4-hydroxy-, methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). D-Proline, 4-hydroxy-, methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
|
-
- HY-N9735
-
|
|
Bacterial
|
Infection
|
|
8-Hydroxy-9,10-diisobutyryloxythymol is a natural monoterpenoid with antibacterial properties. 8-Hydroxy-9,10-diisobutyryloxythymol against S. aureus, S. flexneri, and S. paratyphi-B with MIC values of 6.25 μg/mL .
|
-
- HY-N8114
-
|
|
Others
|
Others
|
|
2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester (compound 3) is a natural product that can be isolated from the dried roots of Rubia cordifolia .
|
-
- HY-W704138R
-
|
|
Endogenous Metabolite
|
Others
|
|
2-Hydroxy-atrazine (Standard) is the analytical standard of 2-Hydroxy-atrazine. This product is intended for research and analytical applications. 2-Hydroxy-atrazine is a non-herbicidal primary photoproduct that results from the hydrolytic dechlorination of atrazine.
|
-
- HY-143966S
-
-
- HY-144199S
-
-
- HY-125944
-
|
|
Mitochondrial Metabolism
|
Others
|
|
Mito-TEMPO is a mitochondria-targeted antioxidant that possesses superoxide and alkyl radical scavenging properties. Mito-TEMPO helps protect against oxidative damage to the mitochondria .
|
-
- HY-W041195S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
3-Hydroxy-3-methylhexanoic acid-d5 is the deuterium labeled 3-Hydroxy-3-methylhexanoic acid (HY-W041195). 3-Hydroxy-3-methylhexanoic acid is a fatty acid that is one of the metabolic products of leukocytes .
|
-
- HY-W002587
-
|
|
Endogenous Metabolite
|
Others
|
|
4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.
|
-
- HY-128452
-
-
- HY-N1625
-
-
- HY-W411442
-
|
|
Others
|
Cancer
|
|
2-Hydroxy-3-methoxychalcone is a methoxy-derivative of 2'-Hydroxychalcone with an anticancer activity .
|
-
- HY-129452
-
|
|
Myosin
|
Others
|
|
(S)-3'-Hydroxy blebbistatin is a myosin II inhibitor and is more water-soluble than Blebbistatin .
|
-
- HY-W051287
-
-
- HY-N3287
-
|
|
Bacterial
|
Infection
|
|
Methyl 3-hydroxy-4,5-dimethoxybenzoate is a gallic acid derivant isolated from myricaria Laxiflora. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H2O2 .
|
-
- HY-143978S
-
-
- HY-145490S1
-
-
- HY-N13673
-
|
|
Others
|
Others
|
|
2-Hydroxy-1,8-dimethoxyxanthone is a natural product .
|
-
- HY-170042A
-
-
- HY-N12004
-
|
|
Others
|
Cancer
|
|
19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively .
|
-
- HY-170045
-
-
- HY-136410
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.
|
-
- HY-N6658
-
|
|
Others
|
Cancer
|
|
6-Hydroxy-4-methylcoumarin (compound 9) is a coumarins secondary metabolites and has anticancer activity .
|
-
- HY-W002339
-
|
|
DNA/RNA Synthesis
|
Others
|
|
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .
|
-
- HY-W005327
-
-
- HY-N7179
-
|
|
Others
|
Others
|
|
7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant .
|
-
- HY-N2748
-
|
|
Others
|
Others
|
|
7-Hydroxy-3-prenylcoumarin is a Coumarins product that can be isolated from the herbs of Coriaria nepalensis .
|
-
- HY-N1588
-
|
|
Others
|
Others
|
|
15-Hydroxy-7-oxodehydroabietic acid is a Diterpenoids product that can be isolated from the herbs of Pinus massoniana .
|
-
- HY-W592871
-
|
10-HDA
|
mTOR
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
10-Hydroxy-2-decenoic acid (10-HDA) is the major lipid component of royal jelly produced by honeybees. 10-Hydroxy-2-decenoic acid has several health-beneficial effects in mammals, such as antitumor activity, anti-inflammatory activity, and antiangiogenic activity. 10-Hydroxy-2-decenoic acid also extends the lifespan of C. elegans .
|
-
- HY-170725
-
-
- HY-N4282
-
|
|
Others
|
Cancer
|
|
8-Hydroxy-7-methoxycoumarin is a phenylpropanoid isolated from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. 8-Hydroxy-7-methoxycoumarin shows cytotoxicity against GLC4 and COLO 320 cancer cell after continuous incubation (4 days) with IC50s of 179 μM and 145 μM .
|
-
- HY-N7160
-
|
|
Src
Apoptosis
|
Cancer
|
|
2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells .
|
-
- HY-N6825R
-
|
|
TRP Channel
Endogenous Metabolite
|
Neurological Disease
|
|
Hydroxy-α-sanshool (Standard) is the analytical standard of Hydroxy-α-sanshool. This product is intended for research and analytical applications. Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s of 69 and 1.1 μM, respectively. Hydroxy-α-sanshool can be used for pain research .
|
-
- HY-W017193S
-
-
- HY-N7516
-
|
|
Parasite
Bacterial
Fungal
|
Infection
|
|
4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity .
|
-
- HY-110286
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer .
|
-
- HY-W105739
-
-
- HY-126857S
-
-
- HY-W654341
-
-
- HY-170042
-
-
- HY-W143303S
-
-
- HY-W016221S1
-
-
- HY-W017100
-
|
6-Methoxysalicylic acid
|
Others
|
Neurological Disease
|
|
2-Hydroxy-6-methoxybenzoic acid can be used for the determination of acetylsalicylic acid and its major metabolite, salicylic acid, in animal plasma. 2-Hydroxy-6-methoxybenzoic acid exhibits significant analgesic effects .
|
-
- HY-N10789
-
|
|
Others
|
Cancer
|
|
(2S)-4'-Hydroxy-7-methoxyflavan is a Flavan. Flavan (4′-hydroxy-7-methoxyflavan) showed an important cytotoxic effect on human leukemic Molt 4 cells .
|
-
- HY-W008150
-
-
- HY-136345
-
|
|
Drug Metabolite
|
Others
|
|
(Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM .
|
-
- HY-N1004
-
|
|
Others
|
Others
|
|
10-Hydroxy-16-epiaffinine is a natural product that can be isolated from the leaves and twigs of Rauvolfia verticillata .
|
-
- HY-W016221
-
|
|
Drug Metabolite
|
Inflammation/Immunology
|
|
6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort .
|
-
- HY-135587
-
|
|
Others
|
Others
|
|
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene (Compound 4) is a reaction product of Raloxifene with tertbutyldimethylsilyl chloride. 4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene is used to synthesize Raloxifene 6-glucuronide .
|
-
- HY-N7557
-
|
|
Others
|
Cancer
|
|
(E)-2'-Hydroxy-3,4-dimethoxychalcone (compound 7) is a Chalcone derivative with orally active. (E)-2'-Hydroxy-3,4-dimethoxychalcone has anti-tumour activities .
|
-
- HY-130801
-
|
5-OHdU
|
Endogenous Metabolite
|
Metabolic Disease
|
|
5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase .
|
-
- HY-121939R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Hydroxy-L-DOPA (Standard) is the analytical standard of 6-Hydroxy-L-DOPA. This product is intended for research and analytical applications. 6-Hydroxy-L-DOPA is a nucleic acid functionalized with electron-donating units .
|
-
- HY-132332S
-
-
- HY-143652S
-
-
- HY-143802S
-
-
- HY-156694
-
|
|
Apoptosis
|
Cancer
|
|
Hydroxy-PP-Me is a potent and specific CBR1 inhibitor with an IC50 of 759 nM. Hydroxy-PP-Me inhibits serum-withdrawal-induced apoptosis. Hydroxy-PP-Me increases As2O3-induced apoptotic cell death compared with As2O3 alone .
|
-
- HY-W654214
-
-
- HY-W015874
-
-
- HY-76981
-
|
|
Others
|
Others
|
|
5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples .
|
-
- HY-125775
-
|
(12S)-12-hydroxy-15-hexadecynoic acid
|
Prostaglandin Receptor
|
Endocrinology
|
|
12(S)-Hydroxy-16-heptadecynoic acid ((12S)-12-Hydroxy-15-hexadecynoic acid) is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase. It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 μM.
|
-
- HY-129890
-
-
- HY-N1743
-
|
|
Phosphatase
|
Metabolic Disease
|
|
1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl), isolated from Broussonetia kazinoki, shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes .
|
-
- HY-P10447
-
|
Fengycin IX; SNA-60-367-3
|
Phospholipase
|
Inflammation/Immunology
|
|
Plipastatin A1 is a lipopeptide with enzyme inhibitory and immunosuppressive activities. Plipastatin A1 is found in Bacillus cereus and inhibits phospholipase A2 (PLA2), PLC, and PLD .
|
-
- HY-166882S
-
-
- HY-108263B
-
|
(R)-CGP52421
|
FLT3
Drug Metabolite
|
Cancer
|
|
(R)-3-Hydroxy Midostaurin ((R)-CGP52421) is a potent kinases inhibitor. (R)-3-Hydroxy Midostaurin is a major metabolite of midostaurin (PKC412; HY-10230) undergoing by the hepatic CYP3A4 enzyme. (R)-3-Hydroxy Midostaurin has the potential for acute myeloid leukemia (AML) .
|
-
- HY-W047428
-
|
|
Others
|
Others
|
|
4-Hydroxy-3,3-dimethylcyclohexanone is a key intermediate for the synthesis of hAChE inhibitor .
|
-
- HY-N2576
-
|
|
Biochemical Assay Reagents
|
Others
|
|
7-Hydroxy-1-naphthalenesulfonate (potassium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W004882
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Hydroxy-1-tetralone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-69341
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-Hydroxy-4-nitrobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001217
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Hydroxy-1-indanone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001570
-
|
|
Biochemical Assay Reagents
|
Others
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3-Hydroxy-1-adamantanecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002597
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(4S)-4-hydroxy-2-pyrrolidinone
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Biochemical Assay Reagents
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Others
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(S)-(-)-4-Hydroxy-2-pyrrolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W016352R
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Biochemical Assay Reagents
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Others
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2-Hydroxy-5-nitrobenzoic acid, 99% (Standard) is the analytical standard of 2-Hydroxy-5-nitrobenzoic acid, 99%. This product is intended for research and analytical applications. 2-Hydroxy-5-nitrobenzoic acid, 99% is used as an HPLC analytical standard, pH indicator, and heavy metal detection agent, and is also used in the study of phenolic compounds oxidation.
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- HY-142098
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- HY-N2487
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Others
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Cancer
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5-Hydroxy-7-acetoxyflavone, an active natural flavone derivative found in various plant sources, modulates several biological activities .
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- HY-N5125
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- HY-W011195
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- HY-N7013
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Others
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Neurological Disease
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Hydroxy-Epsilon-Sanshool is an alkylamide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensates, and its content is important in determinant the pungency intensity of Zanthoxylum bungeanum .
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- HY-108263
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CGP52421
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FLT3
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Cancer
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3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412 .
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- HY-100653A
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Epigenetic Reader Domain
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Cancer
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AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.
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- HY-N12801
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Others
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Others
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3-Hydroxy-1,2-dimethoxyxanthone is a xanthone derivative and can be isolated from Polygala nitida .
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- HY-N8994
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Others
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Cancer
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3-Hydroxy-4',5-dimethoxystilbene is a natural compound found in stem bark of Morus nigra L .
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- HY-136346
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Drug Metabolite
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Cardiovascular Disease
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2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids .
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- HY-135335
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Drug Metabolite
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Metabolic Disease
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3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes .
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- HY-N10914
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Others
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Others
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2-(2'-Hydroxy-4'-methylphenyl)propionic acid is an active compound .
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- HY-W007934
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- HY-N13319
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Others
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Others
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2'-Hydroxy-3',4',6'-trimethoxychalcone is a natural product .
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- HY-N13509
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Others
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Others
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2′-Hydroxy-3′,4′,6′-trimethoxydihydrochalcone is a natural product .
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- HY-142105
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2-Ethyl-2-hydroxybutyric acid
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Endogenous Metabolite
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Metabolic Disease
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2-Ethyl-2-hydroxybutanoic acid (2-Ethyl-2-hydroxybutyric acid) is a hydroxy fatty acid. 2-Ethyl-2-hydroxybutanoic is a metabolite of DEHP (HY-B1945) .
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