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Targets Recommended: NEDD8-activating Enzyme

Results for "414910-30-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-14405A
    Casopitant mesylate

    GW679769B

    Neurokinin Receptor Cytochrome P450 Neurological Disease
    Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of substance P. Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).