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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "442665-87-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-136282

    OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.