Search Result

Targets Recommended:	5 alpha Reductase Aldose Reductase 5-HT Receptor HMG-CoA Reductase (HMGCR) GSNOR FLAP CD73 IFNAR PGC-1α PIKfyve Serotonin Transporter Oct3/4

Results for "5 alpha Reductase Inhibitors" in MCE Product Catalog:

By Targets:	5 alpha Reductase (1) Aldose Reductase (1) HMG-CoA Reductase (HMGCR) (6) IFNAR (2) AChE (1) ADC Cytotoxin (3) Adrenergic Receptor (1) Androgen Receptor (1) Antibiotic (2) Antifolate (6) Apoptosis (7) Aromatase (1) Autophagy (6) Bacterial (7) Bcr-Abl (1) CaMK (1) Casein Kinase (1) DNA/RNA Synthesis (6) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) DYRK (2) Endogenous Metabolite (8) Ephrin Receptor (1) Factor Xa (1) Ferroptosis (2) Fungal (1) GABA Receptor (1) GLUT (1) HIV (1) mGluR (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MMP (1) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (1) p38 MAPK (1) Parasite (3) Phosphatase (1) PKA (1) PKC (1) PROTAC Linker (3) Reactive Oxygen Species (1) Reverse Transcriptase (1) SARS-CoV (1) Sodium Channel (1) Thrombin (1) TNF Receptor (1) Tyrosinase (2) VD/VDR (6) Virus Protease (1)
By Research Areas:	Cancer (34) Cardiovascular Disease (11) Endocrinology (3) Infection (12) Inflammation/Immunology (10) Metabolic Disease (15) Neurological Disease (5)

By Targets:

5 alpha Reductase (1)

Aldose Reductase (1)

HMG-CoA Reductase (HMGCR) (6)

IFNAR (2)

AChE (1)

ADC Cytotoxin (3)

Adrenergic Receptor (1)

Androgen Receptor (1)

Antibiotic (2)

Antifolate (6)

Apoptosis (7)

Aromatase (1)

Autophagy (6)

Bacterial (7)

Bcr-Abl (1)

CaMK (1)

Casein Kinase (1)

DNA/RNA Synthesis (6)

Drug Metabolite (1)

Drug-Linker Conjugates for ADC (1)

DYRK (2)

Endogenous Metabolite (8)

Ephrin Receptor (1)

Factor Xa (1)

Ferroptosis (2)

Fungal (1)

GABA Receptor (1)

GLUT (1)

HIV (1)

mGluR (1)

Microtubule/Tubulin (1)

Mitochondrial Metabolism (1)

MMP (1)

Nucleoside Antimetabolite/Analog (1)

Opioid Receptor (1)

p38 MAPK (1)

Parasite (3)

Phosphatase (1)

PKA (1)

PKC (1)

PROTAC Linker (3)

Reactive Oxygen Species (1)

Reverse Transcriptase (1)

SARS-CoV (1)

Sodium Channel (1)

Thrombin (1)

TNF Receptor (1)

Tyrosinase (2)

VD/VDR (6)

Virus Protease (1)

By Research Areas:

Cancer (34)

Cardiovascular Disease (11)

Endocrinology (3)

Infection (12)

Inflammation/Immunology (10)

Metabolic Disease (15)

Neurological Disease (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas

HY-U00439

Protein kinase inhibitors 1
DYRK Cancer

Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC₅₀ of 74 nM and K_d of 9.5 nM.
HY-18967

Aldose reductase-IN-1
Aldose Reductase Metabolic Disease

Aldose reductase-IN-1 is a inhibitor of aldose reductase with IC50 of 28.9 pM.
HY-U00376

5α-reductase-IN-1
Others Metabolic Disease

5α-reductase-IN-1 is an inhibitor of 5α-reductase, used for the research of patterned alopecia in combination with minoxidil.

*Protein kinase inhibitors* 1**	DYRK	Cancer
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC₅₀ of 74 nM and K_d of 9.5 nM.

*Aldose reductase-IN-1*	Aldose Reductase	Metabolic Disease
Aldose reductase-IN-1 is a inhibitor of aldose reductase with IC50 of 28.9 pM.

*5α-reductase-IN-1*	Others	Metabolic Disease
5α-reductase-IN-1 is an inhibitor of 5α-reductase, used for the research of patterned alopecia in combination with minoxidil.

HY-N1163

Tetrahydroalstonine	Adrenergic Receptor	Endocrinology Neurological Disease
Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist.

HY-131005

Ehp inhibitor 2
Ephrin Receptor Cancer

Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor.
HY-12799

6-Alpha Naloxol
alpha-Naloxol
Opioid Receptor Neurological Disease

6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist closely related to naloxone; a human metabolite of naloxone.

Ehp inhibitor 2	Ephrin Receptor	Cancer
Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor.

*6-Alpha* Naloxol** alpha-Naloxol	Opioid Receptor	Neurological Disease
6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist closely related to naloxone; a human metabolite of naloxone.

HY-125833

Alpha-Naphthoflavone	Aromatase	Cancer
Alpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC₅₀ and a K_i of 0.5 and 0.2 μM, respectively.

HY-N1917

Alpha-Solamarine
Others Metabolic Disease

Alpha-Solamarine is a glycoalkaloid isolated from Solanum aculeastrum.

Alpha-Solamarine	Others	Metabolic Disease
Alpha-Solamarine is a glycoalkaloid isolated from Solanum aculeastrum.

HY-121222

alpha-Bisabolol	Apoptosis	Cancer
alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC₅₀=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells.

HY-121879

SHP836
Phosphatase Cancer

SHP836 is a SHP2 allosteric inhibitor, with an IC₅₀ of 12 μM for the full length SHP2.

SHP836	Phosphatase	Cancer
SHP836 is a SHP2 allosteric inhibitor, with an IC₅₀ of 12 μM for the full length SHP2.

HY-W052512

Antitrypanosomal agent 1	Parasite	Infection
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC₅₀ of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC₅₀=64.8 μM) and T. brucei (EC₅₀=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity.

HY-135402

2'-Ethyl Simvastatin
HMG-CoA Reductase (HMGCR) Cancer Cardiovascular Disease

2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, with HMG-CoA reductase inhibition.
HY-128417

alpha-D-glucose
Endogenous Metabolite Metabolic Disease

alpha-D-glucose is an endogenous metabolite.

2'-Ethyl Simvastatin	HMG-CoA Reductase (HMGCR)	Cancer Cardiovascular Disease
2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, with HMG-CoA reductase inhibition.

alpha-D-glucose	Endogenous Metabolite	Metabolic Disease
alpha-D-glucose is an endogenous metabolite.

HY-125648

Euphorbadienol alpha-Euphorbol	Others	Infection
Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity.

HY-B1761

Santonin
alpha-Santonin
Parasite Infection

Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms.

Santonin alpha-Santonin	Parasite	Infection
Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms.

HY-19373

RWJ-445167 3DP-10017	Thrombin Factor Xa	Cardiovascular Disease
RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with K_i of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

HY-16787

ICA-121431	Sodium Channel	Cardiovascular Disease
ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Na_v) blocker, shows equipotent selectivity for human Na_v1.1 and Na_v1.3 subtypes with IC₅₀ values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Na_v1.2 (IC₅₀=240 nM) and 1,000 fold selectivity against Na_v1.4, Na_v1.6, and the TTX-resistant human Na_v1.5 and Na_v1.8 channels (IC₅₀s >10 µM).

HY-U00439A

*Protein kinase inhibitors* 1 hydrochloride** (E)-5-((2-Oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione hydrochloride	DYRK	Cancer
Protein kinase inhibitors 1 hydrochloride is a potent HIPK2 inhibitor, with IC₅₀s of 136 and 74 nM for HIPK1 and HIPK2, and a K_d of 9.5 nM for HIPK2.

HY-N0255

alpha-Hederin α-Hederin	Apoptosis	Others
alpha-Hederin (α-Hederin) is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation，

HY-N0328

alpha-Mangostin α-Mangostin	Reactive Oxygen Species Apoptosis Bacterial Fungal Virus Protease	Cancer
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-100371

(RS)-MCPG alpha-MCPG	mGluR	Neurological Disease
(RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons.

HY-W012037

8-Hydroxyquinoline hemisulfate 8-Quinolinol hemisulfate	Bacterial Antibiotic	Infection
8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.

HY-100622

Ro 20-0657/000	Bacterial	Infection
Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine.

HY-136346

2-Hydroxy atorvastatin lactone	Drug Metabolite	Others
2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

HY-12836

*IFN alpha-IFNAR-IN-1*	IFNAR	Inflammation/Immunology
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).

HY-B0141A

Alpha-Estradiol Alfatradiol; Epiestradiol; Epiestrol	5 alpha Reductase Endogenous Metabolite	Inflammation/Immunology
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

HY-135813

LtaS-IN-1	Bacterial	Infection
LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely.

HY-125957

A-3 hydrochloride	PKA Casein Kinase CaMK PKC	Others
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (K_i=4.3 µM), casein kinase II (K_i=5.1 µM) and myosin light chain kinase (MLCK) (K_i=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with K_i values of 47 µM and 80 µM, respectively.

HY-123672

Lovastatin hydroxy acid sodium Mevinolinic acid sodium	HMG-CoA Reductase (HMGCR)	Metabolic Disease
Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a K_i of 0.6 nM.

HY-12836A

*IFN alpha-IFNAR-IN-1 hydrochloride*	IFNAR	Inflammation/Immunology
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).

HY-N0700

alpha-Asarone α-Asarone; trans-Asarone	GABA Receptor	Neurological Disease
alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

HY-N0710

alpha-Cyperone α-Cyperone; (+)-α-Cyperone	Endogenous Metabolite	Inflammation/Immunology
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-W013636

2-Ketoglutaric acid alpha-Ketoglutaric acid	Tyrosinase Endogenous Metabolite	Others
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-N0611

alpha-Boswellic acid
α-Boswellic acid
Others Inflammation/Immunology

alpha-Boswellic acid is a natural product.

alpha-Boswellic acid α-Boswellic acid	Others	Inflammation/Immunology
alpha-Boswellic acid is a natural product.

HY-W020044

*DL-alpha-Tocopherol* DL-α-Tocopherol	Ferroptosis	Others
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB.

HY-32348

Doxercalciferol
1.alpha.-Hydroxyvitamin D2
VD/VDR Metabolic Disease Cancer

Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.
HY-141126

Azido-PEG4-alpha-D-mannose
PROTAC Linker Cancer

Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Doxercalciferol 1.alpha.-Hydroxyvitamin D2	VD/VDR	Metabolic Disease Cancer
Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.

*Azido-PEG4-alpha-D-mannose*	PROTAC Linker	Cancer
Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-101918

DS-1040 Tosylate	Others	Cardiovascular Disease
DS-1040 Tosylate is an orally active, selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC₅₀s of 5.92 nM and 8.01 nM for human and rat TAFIa. DS-1040 Tosylate is a fibrinolysis enhancer for thromboembolic diseases.

HY-18728

STF-31
GLUT Autophagy Cancer

STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC₅₀ of 1μM^[1][2].

STF-31	GLUT Autophagy	Cancer
STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC₅₀ of 1μM^[1][2].

HY-15583

Auristatin F	Microtubule/Tubulin ADC Cytotoxin	Cancer
Auristatin F is a potent cytotoxin. Auristatin F, a potent microtubule inhibitor and vascular damaging agent (VDA), can be used in antibody-drug conjugates (ADC).

HY-131089

*MC-VC-PABC-C6-alpha-Amanitin*	Drug-Linker Conjugates for ADC	Cancer
MC-VC-PABC-C6-alpha-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, alpha-Amanitin, linked via the cleavable linker MC-VC-PABC-C6.

HY-P9908

Adalimumab
Anti-Human TNF-alpha, Human Antibody
TNF Receptor Inflammation/Immunology

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
HY-15156

1alpha, 24, 25-Trihydroxy VD2
VD/VDR Metabolic Disease

1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.
HY-N0352

Tuberstemonine
Parasite Infection

Tuberstemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP⁺ reductases (pfFNR).

Adalimumab Anti-Human TNF-alpha, Human Antibody	TNF Receptor	Inflammation/Immunology
Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

1alpha, 24, 25-Trihydroxy VD2	VD/VDR	Metabolic Disease
1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.

Tuberstemonine	Parasite	Infection
Tuberstemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP⁺ reductases (pfFNR).

HY-129605

Ferulenol	Mitochondrial Metabolism	Infection
Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action.

HY-19095

TNP-351	Antifolate	Cancer
TNP-351 is an antifolate. TNP-351, a dihydrofolate reductase (DHFR) inhibitor, has potent antitumor activity against not only leukemia cells but also solid tumor cells in vitro and in vivo.

HY-19931

COH29 RNR Inhibitor COH29	DNA/RNA Synthesis	Cancer
COH29 (RNR Inhibitor COH29) is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity. COH29 inhibits α and β subunit of RNR with IC₅₀s of 16 μM.

HY-122470

Stampidine	Reverse Transcriptase HIV	Infection
Stampidine is a nucleoside reverse transcriptase inhibitor (NRTI) with potent and broad-spectrum anti-HIV activity. Stampidine inhibits the laboratory HIV-1 strain HTLV_IIIB (B-envelope subtype) and primary clinical isolates with IC₅₀s of 1 nM and 2 nM, respectively. Stampidine also inhibits NRTI-resistant primary clinical isolates and NNRTI-resistant clinical isolates with IC₅₀s of 8.7 nM and 11.2 nM, respectively.

HY-140960

*DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000)*	PROTAC Linker	Cancer
DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W013636A

2-Ketoglutaric acid Sodium alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Metabolic Disease
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-112716

*N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride*	Others	Cancer
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK), a trypsin like protease inhibitor, sensitizes HeLa cells to Fas-mediated cell death.

HY-10003

Alfacalcidol 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3	VD/VDR	Metabolic Disease
Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis.

HY-15327

1alpha, 25-Dihydroxy VD2-D6
VD/VDR Metabolic Disease

1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.
HY-11007

GNF-2
Bcr-Abl SARS-CoV Cancer

GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC₅₀ of 138 nM .

HY-107420

AY 9944	Others	Metabolic Disease
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC₅₀=13 nM). AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol.

HY-135957

2'-Azido-2'-deoxyuridine
N3dUrd
DNA/RNA Synthesis Cancer

2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity.

HY-114362

*DL-alpha-Tocopherol methoxypolyethylene glycol succinate* TPGS-750-M	Others	Others
DL-alpha-Tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M) is an amphiphile, acts as a surfactant.

HY-141137

*2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide*	PROTAC Linker	Cancer
2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-16686

α-Tocopherol phosphate alpha-Tocopherol phosphate; TocP; vitamin E phosphate	Others	Others
α-Tocopherol phosphate is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources.

HY-14519A

Methotrexate disodium Amethopterin disodium; CL14377 disodium; WR19039 disodium	Antifolate DNA/RNA Synthesis ADC Cytotoxin Apoptosis	Cancer Inflammation/Immunology
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).

HY-B0510C

Trimethoprim lactate	Antifolate Bacterial	Infection
Trimethoprim lactic is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactic is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim lactic has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment.

HY-14519

Methotrexate Amethopterin; CL14377; WR19039	Antifolate DNA/RNA Synthesis ADC Cytotoxin Apoptosis	Cancer Inflammation/Immunology
Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).

HY-B0510

Trimethoprim	Antifolate Bacterial Antibiotic	Infection
Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment.

HY-10446

Pralatrexate	Antifolate Apoptosis	Cancer
Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor with a K_i of 13.4 pM. Pralatrexate is a substrate for folylpolyglutamate synthetase with improved cellular uptake and retention. Pralatrexate has antitumor activities and has the potential for relapsed/refractory T-cell lymphoma treatment.

HY-136185

Atorvastatin Epoxy Tetrahydrofuran Impurity	Others	Others
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

HY-13249

1alpha-Hydroxy VD4 1α-Hydroxy vitamin D4	VD/VDR	Cancer
1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.

HY-17552

sn-Glycero-3-phosphocholine Choline Alfoscerate; alpha-GPC; L-α-GPC	AChE Endogenous Metabolite	Neurological Disease
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia.

HY-14664

Fluvastatin XU 62-320 free acid	HMG-CoA Reductase (HMGCR) Autophagy	Cancer Cardiovascular Disease
Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

HY-14664A

Fluvastatin sodium XU 62-320	HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis	Cardiovascular Disease Cancer
Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

HY-14664DS

(3S,5R)-Fluvastatin D6 (3S,5R)-XU 62-320 free acid D6	Autophagy	Cancer Cardiovascular Disease
(3S,5R)-Fluvastatin D6 is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

HY-14664AS

Fluvastatin D6 sodium XU 62-320 (D6)	HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Cancer
Fluvastatin D6 sodium (XU 62-320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM.

HY-14664B

(3R,5S)-Fluvastatin (3R,5S)-XU 62-320 free acid	HMG-CoA Reductase (HMGCR) Autophagy	Cancer Cardiovascular Disease
(3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

HY-119974

Caracemide NSC-253272	DNA/RNA Synthesis Bacterial	Cancer Infection
Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide is a novel anticancer agent derived from a hydroxamic acid and has demonstrated to produce severe central nervous system (CNS) toxicity.

HY-113377

L-Glyceric acid	Endogenous Metabolite	Metabolic Disease
L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2.

HY-106014

Tezacitabine	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Apoptosis	Cancer
Tezacitabine is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue. Tezacitabine irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine effectively induces cells apoptotic. Tezacitabine has the potential for leukemias and solid tumors (carcinomas) treatment.

HY-113377A

L-Glyceric acid sodium	Endogenous Metabolite	Metabolic Disease
L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2.

HY-13331

Clascoterone Cortexolone 17 alpha-propionate; Cortexolone 17α-propionate; CB-03-01	Androgen Receptor	Endocrinology
Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.

HY-32337

Tacalcitol 1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3	VD/VDR	Metabolic Disease
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium.

HY-122872

MKK7-COV-9	p38 MAPK	Cancer
MKK7-COV-9 is a potent and selective covalent inhibitor of MKK7 and targets a specific protein–protein interaction of MKK7. MKK7-COV-9 blocks primary B cell activation in response to LPS with an EC₅₀ of 4.98 μM.

HY-120944

BAY-7598	MMP	Inflammation/Immunology
BAY-7598 is a potent, orally bioavailable, and selective MMP12 inhibitor probe with IC₅₀s of 0.085, 0.67 and 1.1 nM for human MMP12, murine MMP12, and rat MMP12, respectively.

HY-104004

Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH	Others	Cancer
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a drug for cancer.

Cat. No.	Product Name	Type

HY-W039911

4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal; PNP-α-D-Gal	Enzyme Substrates
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates.

HY-18593

6-O-α-Maltosyl-β-cyclodextrin 6-O-alpha-D-Maltosyl-beta-cyclodextrin	Biochemical Assay Reagents
6-O-α-Maltosyl-β-cyclodextrin is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.

Cat. No.	Product Name	Target	Research Area

HY-P1948

*Thioredoxin reductase* peptide**	Peptides	Cancer Inflammation/Immunology
Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense.

HY-P1948A

*Thioredoxin reductase* peptide TFA**	Peptides	Others
Thioredoxin reductase peptide TFA corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense.

HY-P1888

*HIF-1 alpha* (556-574)**	Peptides	Cardiovascular Disease
HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.

HY-P1901

*Insulin alpha-chain (1-13)*	Peptides	Metabolic Disease
Insulin alpha-chain (1-13) is a human leucocyte antigen (HLA)-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain.

HY-P1888A

*HIF-1 alpha* (556-574) (TFA)**	Peptides	Cardiovascular Disease
HIF-1 alpha (556-574) TFA is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.

HY-P1912

Alpha 1(I) Collagen (614-639), human
Peptides Endocrinology

Alpha 1(I) Collagen (614-639), human is a peptide fragment of alpha-1 type I collagen.

Cat. No.	Product Name	Target	Research Area

HY-P9908

Adalimumab
Anti-Human TNF-alpha, Human Antibody
TNF Receptor Inflammation/Immunology

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

Cat. No.	Product Name	Target	Category

HY-N1163

Tetrahydroalstonine
Adrenergic Receptor Alkaloids

Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist.
HY-N1917

Alpha-Solamarine
Others Alkaloids Saccharides and Glycosides

Alpha-Solamarine is a glycoalkaloid isolated from Solanum aculeastrum.

HY-121222

alpha-Bisabolol	Apoptosis	Terpenoids and Glycosides
alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC₅₀=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells.

HY-128417

alpha-D-glucose
Endogenous Metabolite Saccharides and Glycosides

alpha-D-glucose is an endogenous metabolite.

HY-125648

Euphorbadienol alpha-Euphorbol	Others	Terpenoids and Glycosides
Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity.

HY-B1761

Santonin
alpha-Santonin
Parasite Terpenoids and Glycosides

Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms.

HY-N0255

alpha-Hederin α-Hederin	Apoptosis	Saccharides and Glycosides Terpenoids and Glycosides
alpha-Hederin (α-Hederin) is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation，

HY-N0328

alpha-Mangostin α-Mangostin	Reactive Oxygen Species Apoptosis Bacterial Fungal Virus Protease	Natural Products
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-B0141A

Alpha-Estradiol Alfatradiol; Epiestradiol; Epiestrol	5 alpha Reductase Endogenous Metabolite	Steroids
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

HY-N0700

alpha-Asarone α-Asarone; trans-Asarone	GABA Receptor	Phenylpropanoids
alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

HY-N0710

alpha-Cyperone α-Cyperone; (+)-α-Cyperone	Endogenous Metabolite	Terpenoids and Glycosides
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-W013636

2-Ketoglutaric acid alpha-Ketoglutaric acid	Tyrosinase Endogenous Metabolite	Acids and Aldehydes
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-N0611

alpha-Boswellic acid
α-Boswellic acid
Others Terpenoids and Glycosides

alpha-Boswellic acid is a natural product.

HY-W020044

*DL-alpha-Tocopherol* DL-α-Tocopherol	Ferroptosis	Phenols
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB.

HY-N0352

Tuberstemonine
Parasite Alkaloids

Tuberstemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP⁺ reductases (pfFNR).

HY-129605

Ferulenol	Mitochondrial Metabolism	Terpenoids and Glycosides
Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action.

HY-W013636A

2-Ketoglutaric acid Sodium alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Acids and Aldehydes
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-17552

sn-Glycero-3-phosphocholine Choline Alfoscerate; alpha-GPC; L-α-GPC	AChE Endogenous Metabolite	Natural Products
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia.

HY-113377

L-Glyceric acid	Endogenous Metabolite	Acids and Aldehydes
L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2.

HY-113377A

L-Glyceric acid sodium	Endogenous Metabolite	Acids and Aldehydes
L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2.

Cat. No.	Product Name	Species	Source

HY-P7470

*Recombinant Human Aldo-keto Reductase* 1C4, His** rHuAldo-keto Reductase 1C4, His; AKR-1C4; Aldo-keto Reductase 1C4	Human	E. coli
Recombinant Human Aldo-keto Reductase 1C4, His is a human recombinant AKR1C4 with a N-Terminal His-tag. Recombinant Human Aldo-keto Reductase 1C4, His is derived from E. coli and corresponding to the amino acids 1-323 of human Aldo-keto Reductase 1C4/AKR1C4.

HY-P7544

Recombinant Mouse Interferon -alpha2
Interferon alpha 2; IFNA2 Protein, Mouse
E. coli
HY-P7469

Recombinant Human Aldo-keto reductase family 1 member C2
rHuAldo-keto Reductase family 1 member C2; AKR-1C2; Aldo-keto Reductase family 1 member C2
Human E. coli

HY-P7493

*Recombinant Human alpha-Parvin, His* rHualpha-Parvin, His; PARVA; MXRA2; alpha-Parvin	Human	E. coli
Recombinant Human alpha-Parvin, His is a recombinant human alpha-Parvin with a His tag at the C-terminus. Alpha-parvin is an essential regulator of actin-dependent processes, such as cell spreading and migration^[1].

HY-P7542

*Recombinant Human Serpin A1/alpha-1-Antitrypsin, His (HEK293-expressed)* rHuSerpin A1/alpha-1-Antitrypsin, His; alpha-1-Antitrypsin; alpha-1 Protease Inhibitor; alpha-1-Antiproteinase; Serpin A1; SERPINA1; AAT; PI	Human	HEK 293
Recombinant Human Serpin A1/alpha-1-Antitrypsin, His (HEK293-expressed) produced in HEK293 cells is a mouse recombinant Serpin A1a with a His tag at the C-terminus^[1]. Alpha-1 Antitrypsin Exerts a hepatoprotective effect on immune-mediated hepatitis and acetaminophen-induced liver injury^[2].

HY-P7463

*Recombinant Human Alpha-Fetoprotein, His (HEK293-expressed)* rHualpha-Fetoprotein, His; AFP; alpha-Fetoprotein	Human	HEK 293
Recombinant Human Alpha-Fetoprotein, His (HEK293-expressed) is a major plasma protein produced by the yolk sac and the fetal liver during fetal development.

HY-P7464

*Recombinant Mouse Alpha-Fetoprotein, His (HEK293-expressed)* rMualpha-Fetoprotein, His; AFP; alpha-Fetoprotein	Mouse	HEK 293
Recombinant Mouse Alpha-Fetoprotein, His (HEK293-expressed) is a mouse recombinant AFP with a His tag at the C-terminus. Recombinant Mouse Alpha-Fetoprotein, His is produced by Mammalian expression system and the target gene encoding Lys19-Val605 is expressed.

HY-P7187

*Recombinant Human GRO alpha/CXCL1* rHuGRO-α/CXCL1; NAP-3; MGSA; Growth-regulated alpha protein	Human	E. coli
Recombinant Human GRO alpha/CXCL1 could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7489

Recombinant Human Alpha 1-Microglobulin, His (HEK293-expressed)
rHualpha 1-Microglobulin, His; AMBP; alpha 1-Microglobulin
Human HEK 293

HY-P7492

*Recombinant Human alpha-Galactosidase A, His (HEK293-expressed)* rHualpha-Galactosidase A, His; GLA; alpha-Galactosidase A	Human	HEK 293
Recombinant Human alpha-Galactosidase A, His (HEK293-expressed), a recombinant human alpha-Galactosidase A produced in HEK293 cells, has a His tag at the C-terminus. Recombinant Human alpha-Galactosidase A is the lysosomal exoglycosidase responsible for the hydrolysis of terminal α-galactosyl residues from glycoconjugates and is the defective enzyme causing Fabry disease^[1].

HY-P7027

Recombinant Human Interleukin-1 alpha rHuIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 alpha	Human	E. coli
Recombinant Human Interleukin-1 alpha is a polypeptidic cytokine that play a key role in inflammation and immunologic reactions.

HY-P7090

*Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2* rMuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Mouse	E. coli
Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2 is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.

HY-P7072

Recombinant Mouse Interleukin-1 alpha rMuIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 alpha	Mouse	E. coli
Recombinant Murine Interleukin-1 alpha, a potent immuno-modulator that mediates a wide range of immune and inflammatory responses.

HY-P7058

*Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2* rHuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Human	E. coli
Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2 is a strong pro-inflammatory cytokine, exhibits high efficacy and tumor cell targeting capability, with low toxicity effects on healthy cells.

HY-P7096

*Recombinant Rat Interleukin-1 alpha* (CHO-expressed)** rRtIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 alpha	Rat	CHO
Recombinant Rat Interleukin-1 alpha (CHO-expressed) is a nonsecreted pro-inflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells and endothelial cells.

HY-P7500

Recombinant Human Alpha-amylase 2B, His (HEK293-expressed)
rHualpha-amylase 2B, His; AMY2B; alpha-amylase 2B
Human HEK 293

HY-P7090A

*Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed)* rMuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Mouse	P. pastoris
Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed) is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.

HY-P7108

*Recombinant Rat Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed)* rRtTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Rat	P. pastoris
Recombinant Rat Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed) is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.

HY-P7058A

*Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed)* rHuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor	Human	P. pastoris
Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2 (P.pastoris-expressed) is a strong pro-inflammatory cytokine, exhibits high efficacy and tumor cell targeting capability, with low toxicity effects on healthy cells.

HY-P7188

*Recombinant Mouse GRO alpha/CXCL1* rMuGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; KC; HSF	Mouse	E. coli
Recombinant Mouse GRO alpha/CXCL1 could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7189

*Recombinant Rat GRO alpha/CXCL1* rRtGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; CINC-1	Rat	E. coli
Recombinant Rat GRO alpha/CXCL1 could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7186

*Recombinant Mouse GRO alpha/CXCL1 (CHO-expressed)* rMuGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; KC; HSF	Mouse	CHO
Recombinant Mouse GRO alpha/CXCL1 (CHO expressed) could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.

HY-P7491

*Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed)* rMualpha-1-antitrypsin 1-1, His; Serpin A1a; alpha-1-antitrypsin 1-1	Mouse	HEK 293
Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed) is a mouse recombinant Serpin A1a with a His tag at the C-terminus. Recombinant Mouse Alpha-1-antitrypsin 1-1, His is produced by Mammalian expression system and the target gene encoding Glu25-Lys413 is expressed.

HY-P7009

Recombinant Human Endostatin (P.pastoris-expressed) rHuEndostatin; Collagen alpha-1(XV) chain	Human	P. pastoris
Recombinant Human Endostatin (P.pastoris-expressed) is an endogenous antiangiogenic peptide with multiple antitumor roles through modulation of various receptors in the plasma membrane, such as suppression of angiogenesis and inhibition of tumor-cell migration and invasion.

HY-P7296

*Recombinant Human Transforming Growth Factor alpha* (CHO-expressed)** rHuTGF-α; ETGF; TGFA	Human	CHO
Recombinant Human Transforming Growth Factor alpha (CHO-expressed) is a potent angiogenic mediator and mitogenic polypeptide.

HY-P7302

Recombinant Bovine Tumor Necrosis Factor alpha rBoTNF-α; Cachectin; TNFA; TNF-α	Bovine	E. coli
Recombinant Bovine Tumor Necrosis Factor alpha is a cytokine involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

HY-P7411

Recombinant Human Transforming Growth Factor alpha rHuTGF-α; ETGF; TGF-type I	Human	E. coli
Recombinant Human Transforming Growth Factor alpha (TGF-α) is a 50-amino-acid polypeptide that binds to the epidermal growth factor (EGF) receptor and stimulates cell growth.

HY-P7490

Recombinant Human alpha-1-acid glycoprotein 2, His (HEK293-expressed)
rHualpha-1-acid glycoprotein 2, His; AGP2; ORM2; alpha-1-acid glycoprotein 2
Human HEK 293

HY-P7303

Recombinant Rhesus Macaque Tumor Necrosis Factor alpha rRhTNF-α; Cachectin; TNF-α; TNFA	Rhesus Macaque	E. coli
Recombinant Rhesus Macaque Tumor Necrosis Factor alpha is a cytokine involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

HY-P7416

*Recombinant Human Tumor Necrosis Factor alpha, His* rHuTNF-α, His; Cachectin; TNFSF2	Human	E. coli
Recombinant Human Tumor Necrosis Factor alpha, His is recombinant human tumor necrosis factor alpha (TNF-α) with his tag. Recombinant Human Tumor Necrosis Factor alpha, a pleiotropic cytokine, is one of the major mediators of inflammation and is involved in a number of infectious and parasitic diseases. It appears to be involved in blood-brain barrier, inflammatory, thrombogenic, and vascular changes associated with brain injury.

HY-P7417

*Recombinant Mouse Tumor Necrosis Factor alpha, His* rMuTNF-α, His; Cachectin; TNFSF2	Mouse	E. coli
Recombinant Mouse Tumor Necrosis Factor alpha, His is recombinant mouse tumor necrosis factor alpha (TNF-α) with his tag. Recombinant Mouse Tumor Necrosis Factor alpha, a major mediator of inflammation, is involved in a number of infectious and parasitic diseases.

HY-P7364

*Recombinant Rat GRO alpha/CXCL1 (HEK293-expressed)* rRtGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; CINC-1; SCYB1	Rat	HEK 293
Recombinant Rat GRO alpha/CXCL1 (HEK293 expressed) is a growth factor as well as a chemoattractant molecule, and is implicated as an oncogenic factor in several tumor types, including prostate and melanoma cancers.

HY-P7304

Recombinant Human Tumor Necrosis Factor beta rHuTNF-β; TNF-β; TNFSF1; Lymphotoxin-alpha	Human	E. coli
Recombinant Human Tumor Necrosis Factor beta exhibits anti-proliferative activity and causes the cellular destruction of tumor cell lines and performs a variety of important roles in immune regulation.

HY-P7374

*Recombinant Human Interleukin-2 Receptor alpha/CD25, Fc Chimera (HEK293-expressed)* rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R alpha; IL-2Rα; IL2RA	Human	HEK 293
Recombinant Human Interleukin-2 Receptor alpha/CD25, Fc Chimera (HEK293-expressed) is a subunit of interleukin-2 receptor, plays a critical role in regulating the IL-2-mediated responses by modulating the affinity of the IL-2R for the ligand.

HY-P7022

*Recombinant Human Interferon-alpha2a* rHuIFN-α2a; IFNA; IFNA2; IFN-a 2a	Human	E. coli
Recombinant Human Interferon-alpha2a is a cytokine belonging to the type I Interferons, acts as a regulatory mediator of the immune response, and also shows antiviral, antitumor activity.

HY-P7023

*Recombinant Human Interferon-alpha2b* rHuIFN-α2b; IFNA; INFA2; IFN-a 2b	Human	E. coli
Recombinant Human Interferon-alpha2b is a cytokine belonging to the type I Interferons, acts as a regulatory mediator of the immune response, and also shows antiviral, antitumor activity.

HY-P7016A

Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Human	E. coli
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor is a hematopoietic growth factor and immune modulator.

HY-P7215

*Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed)* rHuIL-2Rα, His; TAC-antigen; CD25	Human	HEK 293
Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed), also known at Tac antigen and a CD25, is a 42 kDa transmembrane protein. The interleukin 2 receptor alpha, beta and gamma chain constitute the high-affinity IL2 receptor.

HY-P7221

*Recombinant Human Interleukin-5 Receptor alpha* (CHO-expressed)** rHuIL-5Rα; IL-5R; IL-5RA; CD125	Human	CHO
Recombinant Human Interleukin-5 Receptor alpha (CHO-expressed) is a subunit of the Interleukin-5 receptor.

HY-P7377

*Recombinant Human Interleukin-6 Receptor alpha* (Sf9 insect cells-expressed)** rHuIL-6 Receptor α; gp80; CD126	Human	Sf9 insect cells
Recombinant Human Interleukin-6 Receptor alpha (Sf9 insect cells-expressed) is a type I transmembrane glycoprotein that forms a complex with type I transmembrane signal transducer protein gp130 (CD130) and mediates the biological activities of IL-6.

HY-P7069

Recombinant Mouse Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) rMuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Mouse	CHO
Recombinant Mouse Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7094

Recombinant Rat Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) rRtGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Rat	CHO
Recombinant Rat Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7016

Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Human	CHO
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7016B

Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (P.pastoris-expressed) rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim	Human	P. pastoris
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (P.pastoris-expressed) is a hematopoietic growth factor and immune modulator.

HY-P7190

Recombinant Human GRO beta/CXCL2 rHuGRO-β/CXCL2; C-X-C motif chemokine 2; MIP2-alpha; HSF	Human	E. coli
Recombinant Human GRO beta/CXCL2 is a powerful neutrophil chemoattractant and is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis.

HY-P7353

*Recombinant Human FGFR-1 alpha, Fc Chimera (Sf9 insect cells-expressed)* rHuFGFR-1α, Fc Chimera; BFGFR; CD331; FLT-2	Human	Sf9 insect cells
Recombinant Human FGFR-1 alpha, Fc Chimera (Sf9 insect cells-expressed) is a member of fibroblast growth factor receptors.

HY-P7405

*Recombinant Human Signal regulatory protein alpha, His (HEK293-expressed)* rHuSignal regulatory protein α, His; CD172a; SHPS-1; BIT; MYD1	Human	HEK 293
Recombinant Human Signal regulatory protein alpha, His (HEK293-expressed) produced in HEK293 cells is a polypeptide chain amino acids with the C-termimal His tag. Signal regulatory protein alpha (SIRPα, designated CD172a) is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the SIRP/SHPS (CD172) family of the immunoglobulin superfamily.

HY-P7163

Recombinant Human Eotaxin-3/CCL26 rHuEotaxin-3/CCL26; C-C motif chemokine 26; MIP-4-alpha; TSC-1; SCYA26	Human	E. coli
Recombinant Human Eotaxin-3/CCL26 signals exclusively via the CCR3 receptor and has eosinophil-selective chemoattractant activity.

HY-P7256

*Recombinant Human MIP-1 alpha/CCL3* rHuMIP-1α/CCL3; C-C motif chemokine 3; MIP1A; SCYA3	Human	E. coli
Recombinant Human MIP-1 alpha/CCL3 is a member of CC subfamily, exerting various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5.

HY-P7262

*Recombinant Human MIP-3 alpha/CCL20* rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Human	E. coli
Recombinant Human MIP-3 alpha/CCL20 is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7284

*Recombinant Human Stromal-Cell Derived Factor-1 alpha/CXCL12* rHuSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF	Human	E. coli
Recombinant Human Stromal-Cell Derived Factor-1 alpha/CXCL12 is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7285

*Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12* rMuSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF	Mouse	E. coli
Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7286

*Recombinant Rat Stromal-Cell Derived Factor-1 alpha/CXCL12* rRtSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF	Rat	E. coli
Recombinant Rat Stromal-Cell Derived Factor-1 alpha/CXCL12 is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.

HY-P7406

*Recombinant Human Signal regulatory protein alpha, Fc Chimera (HEK293-expressed)* rHuSignal regulatory protein α, Fc Chimera; CD172a; SHPS-1; BIT; MYD1	Human	HEK 293
Recombinant Human Signal regulatory protein alpha (SIRPα), Fc Chimera (HEK293-expressed) produced in HEK293 cells is a polypeptide chain containing 572 amino acids with the C-termimal human IgG1 Fc fragment. Signal regulatory protein alpha (SIRPα, designated CD172a) is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the SIRP/SHPS (CD172) family of the immunoglobulin superfamily.

HY-P7254

*Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed)* rHuMIP-1α/CCL3; C-C motif chemokine 3; MIP1A; SCYA3	Human	CHO
Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed) is a member of CC subfamily, exerting various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5.

HY-P7260

*Recombinant Human MIP-3 alpha/CCL20 (CHO-expressed)* rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Human	CHO
Recombinant Human MIP-3 alpha/CCL20 (CHO-expressed) is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7263

*Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20* rMuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Mouse	E. coli
Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7152

Recombinant Rat CXCL3 (CHO-expressed) rRtCXCL3; C-X-C motif chemokine 3; Cytokine-induced neutrophil chemoattractant 2; CINC-2; MIP2-alpha/beta	Rat	CHO
Recombinant Rat CXCL3 (CHO-expressed) acts as a chemoattractant for neutrophils and is involved in the inflammatory response.

HY-P7255

*Recombinant Mouse Macrophage Inflammatory Protein-1 alpha/CCL3 (HEK293-expressed)* rMuMIP-1α/CCL3; C-C motif chemokine 3; MIP1A; SCYA3	Mouse	HEK 293
Recombinant Mouse Macrophage Inflammatory Protein-1 alpha/CCL3 (HEK293-expressed) is a member of CC subfamily, exerting various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5.

HY-P7261

*Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed)* rRtMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Rat	HEK 293
Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed) is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

HY-P7403

*Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 (CHO-expressed)* rMuSDF-1α/CXCL12; SDF-1; PBSF; C-X-C motif chemokine 12; TLSF	Mouse	CHO
Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 (CHO-expressed) is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.