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Results for "

6724-53-4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Mitochondrial Metabolism (3)
By Research Areas:	Cancer (3) Cardiovascular Disease (3)

3

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Targets Recommended: MDM-2/p53

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Perhexiline maleate 4 Publications Verification	Mitochondrial Metabolism Apoptosis	Cardiovascular Disease Cancer
Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline maleate induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline maleate can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline maleate can be used in the research of cancers, and cardiovascular disease like angina .

Perhexiline-d11 maleate	Mitochondrial Metabolism	Cardiovascular Disease Cancer
Perhexiline-d₁₁ (maleate) is the deuterium labeled Perhexiline maleate. Perhexiline maleate is a potent carnitine palmitoyltransferase 1 (CPT 1) inhibitor with IC50s of 77 and 148 μM for rat heart and liver CPT 1, respectively.

Perhexiline	Mitochondrial Metabolism Apoptosis	Cardiovascular Disease Cancer
Perhexiline is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline can be used in the research of cancers, and cardiovascular disease like angina .

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