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Targets Recommended: NEDD8-activating Enzyme

Results for "680199-06-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-14572

    SN 27858

    DNA Alkylator/Crosslinker Cancer
    PR-104A (SN 27858) is the alcohol metabolite of phosphate prodrug PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity. PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL).